Effects of the Ser326Cys Polymorphism in the DNA Repair OGG1 Gene on Cancer, Cardiovascular, and All-Cause Mortality in the PREDIMED Study: Modulation by Diet

Title:	Effects of the Ser326Cys Polymorphism in the DNA Repair OGG1 Gene on Cancer, Cardiovascular, and All-Cause Mortality in the PREDIMED Study: Modulation by Diet
Authors:	Corella, Dolores Ramirez-Sabio, Judith B. Coltell, Oscar Ortega-Azorín, Carolina Estruch, Ramón Martínez-González, Miguel A. Salas-Salvadó, Jordi Sorlí, José V. Castañer, Olga Arós, Fernando García-Corte, Franscisco J. Serra-Majem, Lluis Gómez-Gracia, Enrique Fiol, Miquel Pintó, Xavier Saez, Guillermo T. Toledo, Estefanía Basora, Josep Fitó, Montserrat Cofán, Montserrat Ros, Emilio Ordovas, Jose M.
UNESCO Clasification:	320610 Enfermedades de la nutrición 320101 Oncología
Keywords:	Cancer Cardiovascular Mortality Nutrigenetics Vegetables
Issue Date:	2018
Journal:	Journal of the Academy of Nutrition and Dietetics
Abstract:	Background Oxidatively induced DNA damage, an important factor in cancer etiology, is repaired by oxyguanine glycosylase 1 (OGG1). The lower repair capacity genotype (homozygote Cys326Cys) in the OGG1-rs1052133 (Ser326Cys) polymorphism has been associated with cancer risk. However, no information is available in relation to cancer mortality, other causes of death, and modulation by diet.
URI:	http://hdl.handle.net/10553/41742
ISSN:	2212-2672
DOI:	10.1016/j.jand.2017.09.025
Source:	Journal of the Academy of Nutrition and Dietetics [ISSN 2212-2672], v. 118 (4), p. 589-605
Appears in Collections:	Artículos

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