Please use this identifier to cite or link to this item:
http://hdl.handle.net/10553/74714
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Tena Pérez, Víctor | en_US |
| dc.contributor.author | Apaza Ticona, Luis | en_US |
| dc.contributor.author | Cabanillas, Alfredo H. | en_US |
| dc.contributor.author | Maderuelo Corral, Santiago | en_US |
| dc.contributor.author | Perles, Josefina | en_US |
| dc.contributor.author | Rosero Valencia, Diego Fernando | en_US |
| dc.contributor.author | Martel Quintana, Antera | en_US |
| dc.contributor.author | Ortega Domenech, Montserrat | en_US |
| dc.contributor.author | Rumbero Sánchez, Ángel | en_US |
| dc.date.accessioned | 2020-10-14T08:51:19Z | - |
| dc.date.available | 2020-10-14T08:51:19Z | - |
| dc.date.issued | 2020 | en_US |
| dc.identifier.issn | 0031-9422 | en_US |
| dc.identifier.other | Scopus | - |
| dc.identifier.uri | http://hdl.handle.net/10553/74714 | - |
| dc.description.abstract | Three carbamidocyclophanes, A, F and V, and carbamidocylindrofridin A were isolated from the cultured freshwater cyanobacterium Cylindrospermum stagnale, collected in the Canary Islands. The chemical structures of these compounds were elucidated through NMR, HRMS and ECD spectroscopy. The absolute configuration of carbamidocyclophane A was confirmed using X-ray-diffraction. All compounds showed apoptotic capacity against the SK-MEL-1, SK-MEL-28 and SK-MEL-31 tumour cells. Carbamidocylindrofridin A had the highest anti-tumour potential, with an IC50 of 1 ± 0.3 μM in the SK-MEL-1 cell line. | en_US |
| dc.language | eng | en_US |
| dc.relation.ispartof | Phytochemistry | en_US |
| dc.source | Phytochemistry [ISSN 0031-9422], v. 180, (Diciembre 2020) | en_US |
| dc.subject | 23 Química | en_US |
| dc.subject | 32 Ciencias médicas | en_US |
| dc.subject.other | Anti-Tumour | en_US |
| dc.subject.other | Carbamidocyclophane | en_US |
| dc.subject.other | Carbamidocylindrofridin | en_US |
| dc.subject.other | Cyanobacterium | en_US |
| dc.subject.other | Cylindrospermum Stagnale | en_US |
| dc.subject.other | Nostocaceae | en_US |
| dc.title | Antitumoral potential of carbamidocyclophanes and carbamidocylindrofridin A isolated from the cyanobacterium Cylindrospermum stagnale BEA 0605B | en_US |
| dc.type | info:eu-repo/semantics/Article | en_US |
| dc.type | Article | en_US |
| dc.identifier.doi | 10.1016/j.phytochem.2020.112529 | en_US |
| dc.identifier.scopus | 85091917505 | - |
| dc.contributor.authorscopusid | 57197446944 | - |
| dc.contributor.authorscopusid | 55320647400 | - |
| dc.contributor.authorscopusid | 57200917147 | - |
| dc.contributor.authorscopusid | 57219252549 | - |
| dc.contributor.authorscopusid | 6507174978 | - |
| dc.contributor.authorscopusid | 57219252800 | - |
| dc.contributor.authorscopusid | 57197486214 | - |
| dc.contributor.authorscopusid | 57213589824 | - |
| dc.contributor.authorscopusid | 57199979254 | - |
| dc.relation.volume | 180 | en_US |
| dc.investigacion | Ciencias | en_US |
| dc.type2 | Artículo | en_US |
| dc.utils.revision | Sí | en_US |
| dc.date.coverdate | Diciembre 2020 | en_US |
| dc.identifier.ulpgc | Sí | es |
| dc.description.sjr | 0,82 | |
| dc.description.jcr | 4,072 | |
| dc.description.sjrq | Q1 | |
| dc.description.jcrq | Q1 | |
| dc.description.scie | SCIE | |
| item.grantfulltext | none | - |
| item.fulltext | Sin texto completo | - |
| crisitem.author.dept | GIR IOCAG: Oceanografía Biológica y Algología Aplicada | - |
| crisitem.author.dept | IU de Oceanografía y Cambio Global | - |
| crisitem.author.orcid | 0000-0002-7450-0505 | - |
| crisitem.author.parentorg | IU de Oceanografía y Cambio Global | - |
| crisitem.author.fullName | Martel Quintana,Antera De Jesús | - |
| Appears in Collections: | Artículos | |
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