Please use this identifier to cite or link to this item:
http://hdl.handle.net/10553/59997
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Turkmen, Serhat | en_US |
dc.contributor.author | Perera, Erick | en_US |
dc.contributor.author | Zamorano, Maria J. | en_US |
dc.contributor.author | Simó-Mirabet, Paula | en_US |
dc.contributor.author | Xu, Hanlin | en_US |
dc.contributor.author | Pérez-Sánchez, Jaume | en_US |
dc.contributor.author | Izquierdo, Marisol | en_US |
dc.date.accessioned | 2019-12-29T18:31:08Z | - |
dc.date.available | 2019-12-29T18:31:08Z | - |
dc.date.issued | 2019 | en_US |
dc.identifier.issn | 1422-0067 | en_US |
dc.identifier.other | Scopus | - |
dc.identifier.uri | http://hdl.handle.net/10553/59997 | - |
dc.description.abstract | Polyunsaturated fatty acids (PUFA) in parental diets play a key role in regulating n-3 LC-PUFA metabolism of the offspring. However, it is not clear whether this metabolic regulation is driven by the precursors presented in the diet or by the parental ability to synthesize them. To elucidate this, broodstocks of gilthead sea bream with different blood expression levels of fads2, which encodes for the rate-limiting enzyme in the n-3 LC-PUFA synthesis pathway, were fed either a diet supplemented with alpha-linolenic acid (ALA, 18:3n-3) or a control diet. The progenies obtained from these four experimental groups were then challenged with a low LC-PUFA diet at the juvenile stage. Results showed that the offspring from parents with high fads2 expression presented higher growth and improved utilization of low n-3 LC-PUFA diets compared to the offspring from parents with low fads2 expression. Besides, an ALA-rich diet during the gametogenesis caused negative effects on the growth of the offspring. The epigenetic analysis demonstrated that methylation in the promoter of fads2 of the offspring was correlated with the parental fads2 expression levels and type of the broodstock diet. | en_US |
dc.language | eng | en_US |
dc.relation | Consumer driven Production: Integrating Innovative Approaches for Competitive and Sustainable Performance across the Mediterranean Aquaculture Value Chain | en_US |
dc.relation.ispartof | International Journal of Molecular Sciences | en_US |
dc.source | International journal of molecular sciences [ISSN 1422-0067], v. 20 (24), 6250 | en_US |
dc.subject | 310502 Piscicultura | en_US |
dc.subject.other | DNA methylation | en_US |
dc.subject.other | Digital droplet PCR | en_US |
dc.subject.other | Modulation of lipid metabolism | en_US |
dc.subject.other | Nutritional programming | en_US |
dc.subject.other | Parental nutrition | en_US |
dc.title | Effects of Dietary Lipid Composition and Fatty Acid Desaturase 2 Expression in Broodstock Gilthead Sea Bream on Lipid Metabolism-Related Genes and Methylation of the fads2 Gene Promoter in Their Offspring | en_US |
dc.type | info:eu-repo/semantics/article | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.3390/ijms20246250 | en_US |
dc.identifier.scopus | 85076488369 | - |
dc.identifier.isi | 000506840100144 | - |
dc.contributor.authorscopusid | 36150331400 | - |
dc.contributor.authorscopusid | 23478009900 | - |
dc.contributor.authorscopusid | 6701451831 | - |
dc.contributor.authorscopusid | 57003155700 | - |
dc.contributor.authorscopusid | 57211362658 | - |
dc.contributor.authorscopusid | 7003402196 | - |
dc.contributor.authorscopusid | 7103111891 | - |
dc.identifier.eissn | 1422-0067 | - |
dc.identifier.issue | 24 | - |
dc.relation.volume | 20 | en_US |
dc.investigacion | Ciencias | en_US |
dc.type2 | Artículo | en_US |
dc.contributor.daisngid | 31655267 | - |
dc.contributor.daisngid | 30906193 | - |
dc.contributor.daisngid | 21764463 | - |
dc.contributor.daisngid | 34750125 | - |
dc.contributor.daisngid | 5053388 | - |
dc.contributor.daisngid | 31500909 | - |
dc.contributor.daisngid | 34295646 | - |
dc.description.numberofpages | 20 | en_US |
dc.utils.revision | Sí | en_US |
dc.contributor.wosstandard | WOS:Turkmen, S | - |
dc.contributor.wosstandard | WOS:Perera, E | - |
dc.contributor.wosstandard | WOS:Zamorano, MJ | - |
dc.contributor.wosstandard | WOS:Simo-Mirabet, P | - |
dc.contributor.wosstandard | WOS:Xu, HL | - |
dc.contributor.wosstandard | WOS:Perez-Sanchez, J | - |
dc.contributor.wosstandard | WOS:Izquierdo, M | - |
dc.date.coverdate | Diciembre 2019 | en_US |
dc.identifier.ulpgc | Sí | es |
dc.description.sjr | 1,317 | |
dc.description.jcr | 4,556 | |
dc.description.sjrq | Q1 | |
dc.description.jcrq | Q1 | |
dc.description.scie | SCIE | |
item.fulltext | Con texto completo | - |
item.grantfulltext | open | - |
crisitem.author.dept | GIR Grupo de Investigación en Acuicultura | - |
crisitem.author.dept | IU de Investigación en Acuicultura Sostenible y Ec | - |
crisitem.author.dept | Departamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos | - |
crisitem.author.dept | GIR Grupo de Investigación en Acuicultura | - |
crisitem.author.dept | IU de Investigación en Acuicultura Sostenible y Ec | - |
crisitem.author.dept | Departamento de Biología | - |
crisitem.author.orcid | 0000-0003-1569-9152 | - |
crisitem.author.orcid | 0000-0003-4297-210X | - |
crisitem.author.parentorg | IU de Investigación en Acuicultura Sostenible y Ec | - |
crisitem.author.parentorg | IU de Investigación en Acuicultura Sostenible y Ec | - |
crisitem.author.fullName | Zamorano Serrano, María Jesús | - |
crisitem.author.fullName | Izquierdo López, María Soledad | - |
crisitem.project.principalinvestigator | Izquierdo López, María Soledad | - |
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