Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/50804
Title: Effect of castration on bone mineral metabolism in rats
Authors: González Rodríguez, M. D.
Sosa Henríquez, M. 
Limiñana Cañal, J. M.
Betancor León, P.
Issue Date: 1990
Publisher: 0014-2565
Journal: Revista clínica española (Ed. impresa) 
Abstract: We have tried to experimentally determine what effect castration is going to have on rats bone and on the main mineral bone regulatory hormones. Twenty ovariectomized female rats and their age and weight matched controls were used. Parathormone, calcitonin, osteocalcin and serum calcium levels were determined as well as mineral bone content and head of femur density. Castration produces, in rat, a marked decrease in circulating calcitonin, parathormone (PTH) and bone density, with no changes in mineral bone concentration. Finally, castration produces a slight increase in osteocalcin serum levels although without a statistical value.
URI: http://hdl.handle.net/10553/50804
ISSN: 0014-2565
Source: Revista clínica española[ISSN 0014-2565],v. 186, p. 436-439
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