Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/50804
Título: Effect of castration on bone mineral metabolism in rats
Autores/as: González Rodríguez, M. D.
Sosa Henríquez, M. 
Limiñana Cañal, Jose Maria 
Betancor León, P.
Clasificación UNESCO: 3201 Ciencias clínicas
Palabras clave: Animal Model
GnRH Antagonist
Orchidectomy
Osteopenia
Osteoporosis
Fecha de publicación: 1990
Publicación seriada: Revista clínica española (Ed. impresa) 
Resumen: We have tried to experimentally determine what effect castration is going to have on rats bone and on the main mineral bone regulatory hormones. Twenty ovariectomized female rats and their age and weight matched controls were used. Parathormone, calcitonin, osteocalcin and serum calcium levels were determined as well as mineral bone content and head of femur density. Castration produces, in rat, a marked decrease in circulating calcitonin, parathormone (PTH) and bone density, with no changes in mineral bone concentration. Finally, castration produces a slight increase in osteocalcin serum levels although without a statistical value.
URI: http://hdl.handle.net/10553/50804
ISSN: 0014-2565
Fuente: Revista Clinica Espanola[ISSN 0014-2565],v. 186 (9), p. 436-439, (Mayo 1990)
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