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Title: Clinical characteristics and risk factors of osteoporosis in postmenopausal women affected by colles fracture. GIUMO study
Authors: Saavedra Santana, P.
Sosa Henríquez, M. 
Torrijos Eslava, A.
Díaz Curiel, M.
Pérez-Cano, R.
Mosquera Martínez, J.
Muñoz-Torres, M.
Alegre López, J.
Valero Díaz De La Madrid, C.
Del Pino Montes, J.
Martínez Díaz-Guerra, G.
Gómez Alonso, C.
Issue Date: 2005
Publisher: 1132-8460
Journal: Revista Española de Enfermedades Metabólicas Óseas 
Abstract: Background. It is a matter of discussion whether or not Colles' fracture is an osteoporotic fracture, or it is more related to traumatism. We studied the distribution of clinical characteristics and risk factors for osteoporosis in a group of postmenopausal women suffering from Colles' fracture and compared them to a control group. Method. Case-control study. We studied 121 postmenopausal Spanish women who had a forearm fracture (Colles' fracture) within the 6 months prior to the study. Three hundred and forty eight women who had no Colles' fracture were the controls. We studied in every woman age, weight, height, actual calcium intake and some gynecological data as age at menarche, age of menopause, fertile years, years since menopause and number of children. We also collected data about some other risk factors for osteoporosis, as consumption of alcohol and tobacco. Results. Colles' patients had more age and less stature than controls and have had the menarche later than controls (13.8 ± 1.9 years vs. 13.2 ± 2.6 years, p = 0.007). We also found an association between Colles' fracture and lactation for more than one year (odds ratio: 1.80, CI 95%: 1.07-3.03). On the other hand, fractured women had a less proportion of bilateral oophorectomy than controls (odds ratio: 0.31, CI 95%: 0.14-0.71). We found a higher prevalence of falls in patients with Colles' fracture (61.0% vs. 29.3%, p < 0.001, odds ratio 3.81 CI 95%: 2.42-5.99), an a lower proportion of treatments for osteoporosis (14.9% vs. 27%, p = 0.007, odds ratio 0.40, CI 95% 0.22-0.74). A family history of fractures almost reached statistically significance. Conclusion. Postmenopausal women suffering from Colles' fracture have less height than controls and had the menarche earlier than them. We found an association between Colles' fracture and lactation during more than a year, and also between Colles' fracture and falls in the last year. Curiously, postmenopausal women with Colles' fracture received less treatment for osteoporosis than controls. A family history of fracture could be another risk factor for Colles' fracture, although the statistical significance was unclear.
ISSN: 1132-8460
DOI: 10.1016/S1132-8460(05)72673-8
Source: Revista Espanola de Enfermedades Metabolicas Oseas[ISSN 1132-8460],v. 14, p. 23-28
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