Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/50577
Title: Novel cytostatic lanostanoid triterpenes from Ganoderma australe
Authors: León, Francisco
Valencia, Meiser
Rivera, Augusto
Nieto, Ivonne
Quintana, J 
Estevez, F 
Bermejo, Jaime
Keywords: Leukemia-Cells
Apoptosis
Sterols
Hl-60
Issue Date: 2003
Publisher: 0018-019X
Journal: Helvetica Chimica Acta 
Abstract: Two new compounds 1 and 2, together with the known sterols ergosterol, 5,6-dehydroergosterol, and ergosterol peroxide, and four polyoxygenated lanostanoid triterpenes named applanoxidic acid A (3), C (4), F (5), and G (6) were isolated from the fungus Ganoderma australe. The structures of the new compounds were elucidated by means of spectroscopic techniques, while the known triterpenoids 3-6 were identified by comparing their spectral data with those reported in the literature. Compounds 1-6 inhibited the viability and growth of the HL-60 cell line.
URI: http://hdl.handle.net/10553/50577
ISSN: 0018-019X
DOI: 10.1002/hlca.200390251
Source: Helvetica Chimica Acta[ISSN 0018-019X],v. 86 (9), p. 3088-3095
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