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https://accedacris.ulpgc.es/handle/10553/50577
| Título: | Novel cytostatic lanostanoid triterpenes from Ganoderma australe | Autores/as: | León, Francisco Valencia, Meiser Rivera, Augusto Nieto, Ivonne Quintana, J Estevez, F Bermejo, Jaime |
Clasificación UNESCO: | 32 Ciencias médicas 2302 Bioquímica |
Palabras clave: | Leukemia-Cells Apoptosis Sterols Hl-60 |
Fecha de publicación: | 2003 | Publicación seriada: | Helvetica Chimica Acta | Resumen: | Two new compounds 1 and 2, together with the known sterols ergosterol, 5,6-dehydroergosterol, and ergosterol peroxide, and four polyoxygenated lanostanoid triterpenes named applanoxidic acid A (3), C (4), F (5), and G (6) were isolated from the fungus Ganoderma australe. The structures of the new compounds were elucidated by means of spectroscopic techniques, while the known triterpenoids 3-6 were identified by comparing their spectral data with those reported in the literature. Compounds 1-6 inhibited the viability and growth of the HL-60 cell line. | URI: | https://accedacris.ulpgc.es/handle/10553/50577 | ISSN: | 0018-019X | DOI: | 10.1002/hlca.200390251 | Fuente: | Helvetica Chimica Acta[ISSN 0018-019X],v. 86 (9), p. 3088-3095 |
| Colección: | Artículos |
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