Identificador persistente para citar o vincular este elemento:
http://hdl.handle.net/10553/50564
| Campo DC | Valor | idioma |
|---|---|---|
| dc.contributor.author | León, Francisco | en_US |
| dc.contributor.author | Brouard Martín,Ignacio | en_US |
| dc.contributor.author | Torres, Fernando | en_US |
| dc.contributor.author | Quintana, Jose | en_US |
| dc.contributor.author | Rivera, Augusto | en_US |
| dc.contributor.author | Estevez, Francisco | en_US |
| dc.contributor.author | Bermejo, Jaime | en_US |
| dc.contributor.other | Torres Andon, Fernando | - |
| dc.contributor.other | Quintana, Jose | - |
| dc.contributor.other | Brouard, Ignacio | - |
| dc.contributor.other | Estevez, Francisco | - |
| dc.contributor.other | Leon, Francisco | - |
| dc.date.accessioned | 2018-11-24T17:01:58Z | - |
| dc.date.available | 2018-11-24T17:01:58Z | - |
| dc.date.issued | 2008 | en_US |
| dc.identifier.issn | 1612-1872 | en_US |
| dc.identifier.uri | http://hdl.handle.net/10553/50564 | - |
| dc.description.abstract | A new phytosphingosine-type ceramide, suillumide (1), was isolated from the EtOH extract of the basidiomycete Suillus luteus (L.) S. E GRAY, along with ten known compounds: ergosta-4,6,8(14),22-tetraen-3-one, ergosterol, ergosterol peroxide, suillin, (E)-3,4,5-trimethoxycinnamic alcohol, 5 alpha,6 alpha-epoxyergosta-8,22-diene-3 beta,7 beta-diol, (R)-1-palmitoylglycerol, ergosta-7,9(11),22-triene-3 beta,5 alpha,6 beta-triol, cerevisterol, and 4-hydroxybenzoic acid. The structure of 1 was determined on the basis of spectroscopic and mass-spectrometric analyses, as well as by chemical methods. Compound 1 and its synthetic diacetyl derivative 2 were tested for their cytotoxic activities against the human melanoma cell line SK-MEL-1. Both drugs showed IC50 values of ca. 10 mu m after 72 h of exposure. | en_US |
| dc.language | eng | en_US |
| dc.relation.ispartof | Chemistry and Biodiversity | en_US |
| dc.source | Chemistry & Biodiversity[ISSN 1612-1872],v. 5 (1), p. 120-125 (Febrero 2008) | en_US |
| dc.subject | 32 Ciencias médicas | en_US |
| dc.subject | 320713 Oncología | en_US |
| dc.subject | 3209 Farmacología | en_US |
| dc.subject.other | Fungi | en_US |
| dc.subject.other | Constituents | en_US |
| dc.subject.other | Granulatus | en_US |
| dc.subject.other | Acids | en_US |
| dc.title | A new ceramide from Suillus luteus and its cytotoxic activity against human melanoma cells | en_US |
| dc.type | info:eu-repo/semantics/Article | en_US |
| dc.type | Article | en_US |
| dc.identifier.doi | 10.1002/cbdv.200890002 | en_US |
| dc.identifier.scopus | 38849104877 | - |
| dc.identifier.isi | 000252838300009 | - |
| dcterms.isPartOf | Chemistry & Biodiversity | - |
| dcterms.source | Chemistry & Biodiversity[ISSN 1612-1872],v. 5 (1), p. 120-125 | - |
| dc.contributor.authorscopusid | 7005039451 | - |
| dc.contributor.authorscopusid | 6603470039 | - |
| dc.contributor.authorscopusid | 55366045300 | - |
| dc.contributor.authorscopusid | 8681043500 | - |
| dc.contributor.authorscopusid | 7102211501 | - |
| dc.contributor.authorscopusid | 7003810011 | - |
| dc.contributor.authorscopusid | 7101636723 | - |
| dc.description.lastpage | 125 | en_US |
| dc.description.firstpage | 120 | en_US |
| dc.relation.volume | 5 | en_US |
| dc.investigacion | Ciencias de la Salud | en_US |
| dc.type2 | Artículo | en_US |
| dc.identifier.wos | WOS:000252838300009 | - |
| dc.contributor.daisngid | 136703 | - |
| dc.contributor.daisngid | 657275 | - |
| dc.contributor.daisngid | 2952604 | - |
| dc.contributor.daisngid | 34941095 | - |
| dc.contributor.daisngid | 128315 | - |
| dc.contributor.daisngid | 244051 | - |
| dc.contributor.daisngid | 384944 | - |
| dc.contributor.daisngid | 5695465 | - |
| dc.identifier.investigatorRID | D-5184-2009 | - |
| dc.identifier.investigatorRID | K-5709-2014 | - |
| dc.identifier.investigatorRID | K-5175-2014 | - |
| dc.identifier.investigatorRID | K-5125-2014 | - |
| dc.identifier.investigatorRID | No ID | - |
| dc.description.numberofpages | 6 | en_US |
| dc.utils.revision | Sí | en_US |
| dc.contributor.wosstandard | WOS:Leon, F | - |
| dc.contributor.wosstandard | WOS:Brouard, I | - |
| dc.contributor.wosstandard | WOS:Torres, F | - |
| dc.contributor.wosstandard | WOS:Quintana, J | - |
| dc.contributor.wosstandard | WOS:Rivera, A | - |
| dc.contributor.wosstandard | WOS:Estevez, F | - |
| dc.contributor.wosstandard | WOS:Bermejo, J | - |
| dc.date.coverdate | Febrero 2008 | en_US |
| dc.identifier.ulpgc | Sí | en_US |
| dc.contributor.buulpgc | BU-MED | en_US |
| dc.description.jcr | 1,659 | - |
| dc.description.jcrq | Q2 | - |
| dc.description.scie | SCIE | - |
| item.fulltext | Sin texto completo | - |
| item.grantfulltext | none | - |
| crisitem.author.dept | GIR IUIBS: Bioquímica | - |
| crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
| crisitem.author.dept | Departamento de Bioquímica y Biología Molecular, Fisiología, Genética e Inmunología | - |
| crisitem.author.dept | GIR IUIBS: Bioquímica | - |
| crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
| crisitem.author.dept | Departamento de Bioquímica y Biología Molecular, Fisiología, Genética e Inmunología | - |
| crisitem.author.orcid | 0000-0001-8225-4538 | - |
| crisitem.author.orcid | 0000-0002-9728-2774 | - |
| crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
| crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
| crisitem.author.fullName | Brouard Martín,Ignacio | - |
| crisitem.author.fullName | Quintana Aguiar, José Martín | - |
| crisitem.author.fullName | Estévez Rosas, Francisco Jesús | - |
| Colección: | Artículos | |
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