Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/49081
Title: Validity of a self-reported diagnosis of depression among participants in a cohort study using the Structured Clinical Interview for DSM-IV (SCID-I)
Authors: Sanchez-Villegas, Almudena 
Schlatter, Javier
Ortuno, Felipe
Lahortiga, Francisca
Pla, Jorge
Benito, Silvia
Martinez Gonzalez, Miguel A.
UNESCO Clasification: 3211 Psiquiatría
Keywords: Sun Cohort
Spanish Population
Physical-Activity
Mental-Disorders
Validation, et al
Issue Date: 2008
Journal: BMC Psychiatry 
Abstract: Background: Depression assessment in population studies is usually based on depressive symptoms scales. However, the use of scales could lead to the choice of an arbitrary cut-off point depending on the sample characteristics and on the patient diagnosis. Thus, the use of a medical diagnosis of depression could be a more appropriate approach. Objective: To validate a self-reported physician diagnosis of depression using the Structured Clinical Interview for DSM-IV (SCID-I) as Gold Standard and to assess the factors associated to a valid self-reported diagnosis. Methods: The SUN Project is a cohort study based on university graduates followed-up through postal questionnaires. The response to the question included in the questionnaire: Have you ever been diagnosed of depression by a physician? was compared to that obtained through the SCID-I applied by a psychiatrist or a clinical psychologist. The percentages of confirmed depression and non-depression were assessed for the overall sample and according to several characteristics. Logistic regression models were fitted to ascertain the association between different factors and a correct classification regarding depression status. Results: The percentage of confirmed depression was 74.2%; 95% confidence interval (95% CI) = 63.3-85.1. Out of 42 participants who did not report a depression diagnosis in the questionnaire, 34 were free of the disease (%confirmed non-depression = 81.1%; 95% CI = 69.1-92.9). The probability of being a true positive was higher among ex-smokers and non-smokers and among those overweight or obese but the differences were not statistically significant. Conclusion: The validity of a self-reported diagnosis of depression in the SUN cohort is adequate. Thus, this question about depression diagnosis could be used in further investigations regarding this disease in this graduate cohort study. © 2008 Sanchez-Villegas et al; licensee BioMed Central Ltd.
URI: http://hdl.handle.net/10553/49081
ISSN: 1471-244X
DOI: 10.1186/1471-244X-8-43
Source: BMC Psychiatry,v. 8 (43)
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