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Title: Bilirubin-albumin binding in term newborns on total parenteral nutrition
Authors: Domínguez Ortega, F.
González Azpeitia, G. 
Domenech Martínez, E.
UNESCO Clasification: 32 Ciencias médicas
320110 Pediatría
Keywords: Newborn
Parenteral nutrition
Issue Date: 1997
Journal: Nutrición Hospitalaria 
Abstract: We evaluate the influence of plasma lipid levels supplied in parenteral nutrition, on the bilirubin-albumin binding of 12 term newborns with severe pathologies. As controls we selected 2 groups of an equal number o newborns who were receiving maternal or artificial lactation. The reserved albumin binding capacity decreased in newborns subjected to parenteral nutrition (52.3 versus 72.9/73.5). This decrease correlated positively with greater concentrations of free fatty acids (r = 0.9234, p < 0.001), cholesterol (r = 0.9049, p < 0.001), and triglycerides (r = 0.8802, p < 0.001). The clear influence of the studied lipid parameters on the bilirubin albumin binding, invites us to consider the systematic use of heparin for the mobilization of lipoprotein-lipase from the vascular endothelium and to promote a better management of lipids in term newborns, especially if there is an important hyperbilirubinemia.
ISSN: 0212-1611
Source: Nutrición hospitalaria : organo oficial de la Sociedad Española de Nutrición Parenteral y Enteral[ISSN 0212-1611],v. 12, p. 201-205
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