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Title: | Collagen dysplasia in a litter of Garafiano shepherd dogs | Authors: | Rodríguez Guisado, Francisco Herráez Thomas, Pedro Manuel Espinosa De Los Monteros Y Zayas, Antonio Calabuig, P Rodríguez Navarro, José Luis |
UNESCO Clasification: | 310902 Genética | Keywords: | Ehlers-Danlos Syndrome Skin Fibrillogenesis |
Issue Date: | 1996 | Publisher: | 0931-184X | Journal: | Journal of Veterinary Medicine Series A: Physiology Pathology Clinical Medicine | Abstract: | A connective tissue disease resembling the human Ehlers-Danlos syndrome is reported in three Garafiano shepherd dogs from the same litter. The clinical signs included skin hyperextensibility and fragility, joint laxity, and ocular lesions. Microscopical studies showed abnormalities in the packing of collagen in fibrils and fibres in the skin. Systemic connective tissue defects were demonstrated in one necropsied puppy. | URI: | http://hdl.handle.net/10553/43400 | ISSN: | 0931-184X | DOI: | 10.1111/j.1439-0442.1996.tb00482.x | Source: | Journal of Veterinary Medicine Series A: Physiology Pathology Clinical Medicine [ISSN 0931-184X], v. 43, p. 509-512 |
Appears in Collections: | Artículos |
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