Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/43400
Title: Collagen dysplasia in a litter of Garafiano shepherd dogs
Authors: Rodríguez Guisado, Francisco 
Herráez Thomas, Pedro Manuel 
Espinosa De Los Monteros Y Zayas, Antonio 
Calabuig, P
Rodríguez Navarro, José Luis 
UNESCO Clasification: 310902 Genética
Keywords: Ehlers-Danlos Syndrome
Skin
Fibrillogenesis
Issue Date: 1996
Publisher: 0931-184X
Journal: Journal of Veterinary Medicine Series A: Physiology Pathology Clinical Medicine 
Abstract: A connective tissue disease resembling the human Ehlers-Danlos syndrome is reported in three Garafiano shepherd dogs from the same litter. The clinical signs included skin hyperextensibility and fragility, joint laxity, and ocular lesions. Microscopical studies showed abnormalities in the packing of collagen in fibrils and fibres in the skin. Systemic connective tissue defects were demonstrated in one necropsied puppy.
URI: http://hdl.handle.net/10553/43400
ISSN: 0931-184X
DOI: 10.1111/j.1439-0442.1996.tb00482.x
Source: Journal of Veterinary Medicine Series A: Physiology Pathology Clinical Medicine [ISSN 0931-184X], v. 43, p. 509-512
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