Identificador persistente para citar o vincular este elemento:
http://hdl.handle.net/10553/24028
Campo DC | Valor | idioma |
---|---|---|
dc.contributor.author | Julve Parreño, J.M. | en_US |
dc.contributor.author | Huet, E. | en_US |
dc.contributor.author | Fernández-del-Carmen, A. | en_US |
dc.contributor.author | Segura, A. | en_US |
dc.contributor.author | Venturi, M. | en_US |
dc.contributor.author | Gandía, A. | en_US |
dc.contributor.author | Pan, W.-S | en_US |
dc.contributor.author | Albaladejo, I. | en_US |
dc.contributor.author | Forment, J. | en_US |
dc.contributor.author | Pla, D. | en_US |
dc.contributor.author | Wigdorovitz, A. | en_US |
dc.contributor.author | Calvete, J.J. | en_US |
dc.contributor.author | Gutiérrez Cabrera, Carlos Javier | en_US |
dc.contributor.author | Gutiérrez, J.M. | en_US |
dc.contributor.author | Granell, A. | en_US |
dc.contributor.author | Orzáez, D. | en_US |
dc.date.accessioned | 2017-10-19T02:31:29Z | - |
dc.date.accessioned | 2018-03-08T13:06:36Z | - |
dc.date.available | 2017-10-19T02:31:29Z | - |
dc.date.available | 2018-03-08T13:06:36Z | - |
dc.date.issued | 2017 | en_US |
dc.identifier.issn | 1467-7644 | en_US |
dc.identifier.uri | http://hdl.handle.net/10553/24028 | - |
dc.description.abstract | Antivenoms developed from the plasma of hyperimmunized animals are the only effective treatment available against snakebite envenomation but shortage of supply contributes to the high morbidity and mortality toll of this tropical disease. We describe a synthetic biology approach to affordable and cost-effective antivenom production based on plant-made recombinant polyclonal antibodies (termed pluribodies). The strategy takes advantage of virus superinfection exclusion to induce the formation of somatic expression mosaics in agroinfiltrated plants, which enables the expression of complex antibody repertoires in a highly reproducible manner. | en_US |
dc.format | application/pdf | es |
dc.language | eng | en_US |
dc.relation | MINECO and ERDF (project grants IPT2011-0720-010000, BIO2013-42193-R and BIO2016-78601-R) | en_US |
dc.relation | grant BFU2013-42833-P from the Spanish Ministry of Economy and Competitiveness | en_US |
dc.relation.ispartof | Plant Biotechnology Journal | en_US |
dc.rights | by-nc-nd | es |
dc.source | Plant Biotechnology Journal [ISSN 1467-7644], v. 16(3), p. 727-736 | en_US |
dc.subject | 3109 Ciencias veterinarias | en_US |
dc.subject | 3108 Fitopatología | en_US |
dc.subject.other | Recombinant polyclonal antibodies | en_US |
dc.subject.other | Molecular pharming | en_US |
dc.subject.other | Snake antivenoms | en_US |
dc.title | A synthetic biology approach for consistent production of plant-made recombinant polyclonal antibodies against snake venom toxins | en_US |
dc.type | info:eu-repo/semantics/Article | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1111/pbi.12823 | en_US |
dc.identifier.scopus | 85030123782 | - |
dc.identifier.isi | 000425452300003 | - |
dc.contributor.authorscopusid | 57195922263 | - |
dc.contributor.authorscopusid | 57195919101 | - |
dc.contributor.authorscopusid | 22134178400 | - |
dc.contributor.authorscopusid | 8851696200 | - |
dc.contributor.authorscopusid | 57195923199 | - |
dc.contributor.authorscopusid | 55585946300 | - |
dc.contributor.authorscopusid | 57195920119 | - |
dc.contributor.authorscopusid | 57200634443 | - |
dc.contributor.authorscopusid | 6507618274 | - |
dc.contributor.authorscopusid | 23025743900 | - |
dc.contributor.authorscopusid | 6602679344 | - |
dc.contributor.authorscopusid | 26643263500 | - |
dc.contributor.authorscopusid | 7202545218 | - |
dc.contributor.authorscopusid | 34975051900 | - |
dc.contributor.authorscopusid | 6603864813 | - |
dc.contributor.authorscopusid | 6507384919 | - |
dc.identifier.crisid | -;-;-;-;-;-;-;-;-;-;-;-;1327;-;-;- | - |
dc.investigacion | Ciencias | en_US |
dc.project.reference | IPT-2011-0720-010000;BIO2013-42193-R;BIO2016-78601-R;IBFU2013-42833-P | es |
dc.rights.accessrights | info:eu-repo/semantics/openAccess | es |
dc.type2 | Artículo | en_US |
dc.contributor.daisngid | 1605515 | - |
dc.contributor.daisngid | 18330846 | - |
dc.contributor.daisngid | 3837554 | - |
dc.contributor.daisngid | 616701 | - |
dc.contributor.daisngid | 14241642 | - |
dc.contributor.daisngid | 12379558 | - |
dc.contributor.daisngid | 2684555 | - |
dc.contributor.daisngid | 7270799 | - |
dc.contributor.daisngid | 1228044 | - |
dc.contributor.daisngid | 1055940 | - |
dc.contributor.daisngid | 778010 | - |
dc.contributor.daisngid | 31412 | - |
dc.contributor.daisngid | 475608 | - |
dc.contributor.daisngid | 9990 | - |
dc.contributor.daisngid | 226869 | - |
dc.contributor.daisngid | 844944 | - |
dc.identifier.external | -;-;-;-;-;-;-;-;-;-;-;-;1327;-;-;- | - |
dc.identifier.external | WOS:000425452300003 | - |
dc.utils.revision | Sí | en_US |
dc.contributor.wosstandard | WOS:Parreno, JMJ | - |
dc.contributor.wosstandard | WOS:Huet, E | - |
dc.contributor.wosstandard | WOS:Fernandez-del-Carmen, A | - |
dc.contributor.wosstandard | WOS:Segura, A | - |
dc.contributor.wosstandard | WOS:Venturi, M | - |
dc.contributor.wosstandard | WOS:Gandia, A | - |
dc.contributor.wosstandard | WOS:Pan, WS | - |
dc.contributor.wosstandard | WOS:Albaladejo, I | - |
dc.contributor.wosstandard | WOS:Forment, J | - |
dc.contributor.wosstandard | WOS:Pla, D | - |
dc.contributor.wosstandard | WOS:Wigdorovitz, A | - |
dc.contributor.wosstandard | WOS:Calvete, JJ | - |
dc.contributor.wosstandard | WOS:Gutierrez, C | - |
dc.contributor.wosstandard | WOS:Gutierrez, JM | - |
dc.contributor.wosstandard | WOS:Granell, A | - |
dc.contributor.wosstandard | WOS:Orzaez, D | - |
dc.date.coverdate | Marzo 2018 | en_US |
dc.identifier.supplement | -;-;-;-;-;-;-;-;-;-;-;-;1327;-;-;- | - |
dc.identifier.supplement | -;-;-;-;-;-;-;-;-;-;-;-;1327;-;-;- | - |
dc.identifier.supplement | -;-;-;-;-;-;-;-;-;-;-;-;1327;-;-;- | - |
dc.identifier.supplement | -;-;-;-;-;-;-;-;-;-;-;-;1327;-;-;- | - |
dc.identifier.ulpgc | Sí | en_US |
dc.contributor.buulpgc | BU-BAS | en_US |
dc.description.sjr | 2,891 | |
dc.description.jcr | 6,305 | |
dc.description.sjrq | Q1 | |
dc.description.jcrq | Q1 | |
dc.description.scie | SCIE | |
item.grantfulltext | open | - |
item.fulltext | Con texto completo | - |
crisitem.author.dept | GIR IUIBS: Medicina Veterinaria e Investigación Terapéutica | - |
crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.orcid | 0000-0003-0764-7408 | - |
crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.fullName | Gutiérrez Cabrera,Carlos Javier | - |
Colección: | Artículos |
Citas SCOPUSTM
31
actualizado el 24-nov-2024
Citas de WEB OF SCIENCETM
Citations
30
actualizado el 24-nov-2024
Visitas
119
actualizado el 23-nov-2024
Descargas
45
actualizado el 23-nov-2024
Google ScholarTM
Verifica
Altmetric
Comparte
Exporta metadatos
Los elementos en ULPGC accedaCRIS están protegidos por derechos de autor con todos los derechos reservados, a menos que se indique lo contrario.