Identificador persistente para citar o vincular este elemento:
http://hdl.handle.net/10553/18969
| Campo DC | Valor | idioma |
|---|---|---|
| dc.contributor.author | Mirecki Garrido, Mercedes de | en_US |
| dc.contributor.author | Guerra, Borja | en_US |
| dc.contributor.author | Mateos-Díaz, Carlos | en_US |
| dc.contributor.author | Jímenez-Monzón, Roberto | en_US |
| dc.contributor.author | Diaz-Chico, Bonifacio | en_US |
| dc.contributor.author | Díaz-Chico, Juan C. | en_US |
| dc.contributor.author | Fernández-Pérez, Leandro | en_US |
| dc.contributor.other | Diaz-Chico, Juan | - |
| dc.contributor.other | Guerra, Borja | - |
| dc.contributor.other | Fernandez-Perez, Leandro | - |
| dc.contributor.other | Mirecki-Garrido, Mercedes | - |
| dc.date.accessioned | 2016-11-03T03:31:02Z | |
| dc.date.accessioned | 2018-03-16T09:12:51Z | - |
| dc.date.available | 2016-11-03T03:31:02Z | |
| dc.date.available | 2018-03-16T09:12:51Z | - |
| dc.date.issued | 2012 | en_US |
| dc.identifier.issn | 1424-8247 | en_US |
| dc.identifier.uri | http://hdl.handle.net/10553/18969 | - |
| dc.description.abstract | GH is main regulator of body growth and composition, somatic development, intermediate metabolism and gender-dependent dimorphism in mammals. The liver is a direct target of estrogens because it expresses estrogen receptors which are connected with development, lipid metabolism and insulin sensitivity, hepatic carcinogenesis, protection from drug-induced toxicity and fertility. In addition, estrogens can modulate GH actions in liver by acting centrally, regulating pituitary GH secretion, and, peripherally, by modulating GHR-JAK2-STAT5 signalling pathway | en_US |
| dc.description.abstract | GH is main regulator of body growth and composition, somatic development, intermediate metabolism and gender-dependent dimorphism in mammals. The liver is a direct target of estrogens because it expresses estrogen receptors which are connected with development, lipid metabolism and insulin sensitivity, hepatic carcinogenesis, protection from drug-induced toxicity and fertility. In addition, estrogens can modulate GH actions in liver by acting centrally, regulating pituitary GH secretion, and, peripherally, by modulating GHR-JAK2-STAT5 signalling pathway | en_US |
| dc.format | application/pdf | es |
| dc.language | eng | en_US |
| dc.relation.ispartof | Pharmaceuticals | en_US |
| dc.rights | by-nc-nd | es |
| dc.source | Pharmaceuticals [ISSN 1424-8247], v. 5(7), p. 758-778 | en_US |
| dc.subject | 320101 Oncología | en_US |
| dc.subject.other | Growth hormone | en_US |
| dc.subject.other | 17β-estradiol | en_US |
| dc.subject.other | Liver | en_US |
| dc.subject.other | Growth | en_US |
| dc.subject.other | Metabolism | en_US |
| dc.subject.other | STAT5 | en_US |
| dc.title | The Influence of Estrogens on the Biological and TherapeuticActions of Growth Hormone in the Liver | en_US |
| dc.type | info:eu-repo/semantics/article | en_US |
| dc.type | Article | en_US |
| dc.identifier.doi | 10.3390/ph5070758 | en_US |
| dc.identifier.scopus | 84864701169 | - |
| dc.identifier.isi | 000437591100006 | - |
| dcterms.isPartOf | Pharmaceuticals | |
| dcterms.source | Pharmaceuticals[ISSN 1424-8247],v. 5 (7), p. 758-778 | |
| dc.contributor.authorscopusid | 55221793700 | - |
| dc.contributor.authorscopusid | 7006442271 | - |
| dc.contributor.authorscopusid | 6503885823 | - |
| dc.contributor.authorscopusid | 55329696800 | - |
| dc.contributor.authorscopusid | 25723175700 | - |
| dc.contributor.authorscopusid | 6701492347 | - |
| dc.contributor.authorscopusid | 6506777525 | - |
| dc.identifier.crisid | -;20507;-;-;-;1996;2167 | |
| dc.description.lastpage | 778 | en_US |
| dc.description.firstpage | 758 | en_US |
| dc.relation.volume | 5 | en_US |
| dc.investigacion | Ciencias de la Salud | en_US |
| dc.rights.accessrights | Acceso libre | es |
| dc.type2 | Artículo | en_US |
| dc.identifier.wos | WOS:000437591100006 | - |
| dc.contributor.daisngid | 4588303 | - |
| dc.contributor.daisngid | 12155528 | - |
| dc.contributor.daisngid | 909211 | - |
| dc.contributor.daisngid | 6799819 | - |
| dc.contributor.daisngid | 19892441 | - |
| dc.contributor.daisngid | 4287772 | - |
| dc.contributor.daisngid | 1724161 | - |
| dc.contributor.daisngid | 749099 | - |
| dc.contributor.daisngid | 795544 | - |
| dc.identifier.investigatorRID | H-1527-2015 | - |
| dc.identifier.investigatorRID | G-9739-2015 | - |
| dc.identifier.investigatorRID | H-1493-2015 | - |
| dc.identifier.investigatorRID | No ID | - |
| dc.utils.revision | Sí | en_US |
| dc.contributor.wosstandard | WOS:de Mirecki-Garrido, M | - |
| dc.contributor.wosstandard | WOS:Guerra, B | - |
| dc.contributor.wosstandard | WOS:Mateos-Diaz, C | - |
| dc.contributor.wosstandard | WOS:Jimenez-Monzon, R | - |
| dc.contributor.wosstandard | WOS:Diaz-Chico, N | - |
| dc.contributor.wosstandard | WOS:Diaz-Chico, JC | - |
| dc.contributor.wosstandard | WOS:Fernandez-Perez, L | - |
| dc.date.coverdate | Julio 2012 | en_US |
| dc.identifier.supplement | -;20507;-;-;-;1996;2167 | - |
| dc.identifier.supplement | -;20507;-;-;-;1996;2167 | - |
| dc.identifier.supplement | -;20507;-;-;-;1996;2167 | - |
| dc.identifier.ulpgc | Sí | en_US |
| dc.contributor.buulpgc | BU-MED | en_US |
| dc.description.sjr | 0,535 | |
| dc.description.sjrq | Q2 | |
| dc.description.esci | ESCI | |
| item.grantfulltext | open | - |
| item.fulltext | Con texto completo | - |
| crisitem.author.dept | GIR IUIBS: Farmacología Molecular y Traslacional | - |
| crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
| crisitem.author.dept | Departamento de Ciencias Clínicas | - |
| crisitem.author.dept | GIR IUIBS: Bioquímica | - |
| crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
| crisitem.author.dept | Departamento de Bioquímica y Biología Molecular, Fisiología, Genética e Inmunología | - |
| crisitem.author.dept | GIR IUIBS: Bioquímica | - |
| crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
| crisitem.author.dept | Departamento de Bioquímica y Biología Molecular, Fisiología, Genética e Inmunología | - |
| crisitem.author.dept | GIR IUIBS: Farmacología Molecular y Traslacional | - |
| crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
| crisitem.author.dept | Departamento de Ciencias Clínicas | - |
| crisitem.author.orcid | 0000-0003-0488-6307 | - |
| crisitem.author.orcid | 0000-0003-4355-5682 | - |
| crisitem.author.orcid | 0000-0002-0944-990X | - |
| crisitem.author.orcid | 0000-0002-0944-990X | - |
| crisitem.author.orcid | 0000-0001-7802-465X | - |
| crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
| crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
| crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
| crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
| crisitem.author.fullName | De Mirecki Garrido, Mercedes | - |
| crisitem.author.fullName | Guerra Hernández, Carlos Borja | - |
| crisitem.author.fullName | Díaz Chico, Juan Carlos | - |
| crisitem.author.fullName | Díaz Chico, Juan Carlos | - |
| crisitem.author.fullName | Fernández Pérez, Leandro Francisco | - |
| Colección: | Artículos | |
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