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Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/18969
DC FieldValueLanguage
dc.contributor.authorMirecki Garrido, Mercedes deen_US
dc.contributor.authorGuerra, Borjaen_US
dc.contributor.authorMateos-Díaz, Carlosen_US
dc.contributor.authorJímenez-Monzón, Robertoen_US
dc.contributor.authorDiaz-Chico, Bonifacioen_US
dc.contributor.authorDíaz-Chico, Juan C.en_US
dc.contributor.authorFernández-Pérez, Leandroen_US
dc.contributor.otherDiaz-Chico, Juan-
dc.contributor.otherGuerra, Borja-
dc.contributor.otherFernandez-Perez, Leandro-
dc.contributor.otherMirecki-Garrido, Mercedes-
dc.date.accessioned2016-11-03T03:31:02Z
dc.date.accessioned2018-03-16T09:12:51Z-
dc.date.available2016-11-03T03:31:02Z
dc.date.available2018-03-16T09:12:51Z-
dc.date.issued2012en_US
dc.identifier.issn1424-8247en_US
dc.identifier.urihttp://hdl.handle.net/10553/18969-
dc.description.abstractGH is main regulator of body growth and composition, somatic development, intermediate metabolism and gender-dependent dimorphism in mammals. The liver is a direct target of estrogens because it expresses estrogen receptors which are connected with development, lipid metabolism and insulin sensitivity, hepatic carcinogenesis, protection from drug-induced toxicity and fertility. In addition, estrogens can modulate GH actions in liver by acting centrally, regulating pituitary GH secretion, and, peripherally, by modulating GHR-JAK2-STAT5 signalling pathwayen_US
dc.description.abstractGH is main regulator of body growth and composition, somatic development, intermediate metabolism and gender-dependent dimorphism in mammals. The liver is a direct target of estrogens because it expresses estrogen receptors which are connected with development, lipid metabolism and insulin sensitivity, hepatic carcinogenesis, protection from drug-induced toxicity and fertility. In addition, estrogens can modulate GH actions in liver by acting centrally, regulating pituitary GH secretion, and, peripherally, by modulating GHR-JAK2-STAT5 signalling pathwayen_US
dc.formatapplication/pdfes
dc.languageengen_US
dc.relation.ispartofPharmaceuticalsen_US
dc.rightsby-nc-ndes
dc.sourcePharmaceuticals [ISSN 1424-8247], v. 5(7), p. 758-778en_US
dc.subject320101 Oncologíaen_US
dc.subject.otherGrowth hormoneen_US
dc.subject.other17β-estradiolen_US
dc.subject.otherLiveren_US
dc.subject.otherGrowthen_US
dc.subject.otherMetabolismen_US
dc.subject.otherSTAT5en_US
dc.titleThe Influence of Estrogens on the Biological and TherapeuticActions of Growth Hormone in the Liveren_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.typeArticleen_US
dc.identifier.doi10.3390/ph5070758en_US
dc.identifier.scopus84864701169-
dc.identifier.isi000437591100006-
dcterms.isPartOfPharmaceuticals
dcterms.sourcePharmaceuticals[ISSN 1424-8247],v. 5 (7), p. 758-778
dc.contributor.authorscopusid55221793700-
dc.contributor.authorscopusid7006442271-
dc.contributor.authorscopusid6503885823-
dc.contributor.authorscopusid55329696800-
dc.contributor.authorscopusid25723175700-
dc.contributor.authorscopusid6701492347-
dc.contributor.authorscopusid6506777525-
dc.identifier.crisid-;20507;-;-;-;1996;2167
dc.description.lastpage778en_US
dc.description.firstpage758en_US
dc.relation.volume5en_US
dc.investigacionCiencias de la Saluden_US
dc.rights.accessrightsAcceso librees
dc.type2Artículoen_US
dc.identifier.wosWOS:000437591100006-
dc.contributor.daisngid4588303-
dc.contributor.daisngid12155528-
dc.contributor.daisngid909211-
dc.contributor.daisngid6799819-
dc.contributor.daisngid19892441-
dc.contributor.daisngid4287772-
dc.contributor.daisngid1724161-
dc.contributor.daisngid749099-
dc.contributor.daisngid795544-
dc.identifier.investigatorRIDH-1527-2015-
dc.identifier.investigatorRIDG-9739-2015-
dc.identifier.investigatorRIDH-1493-2015-
dc.identifier.investigatorRIDNo ID-
dc.utils.revisionSíen_US
dc.contributor.wosstandardWOS:de Mirecki-Garrido, M-
dc.contributor.wosstandardWOS:Guerra, B-
dc.contributor.wosstandardWOS:Mateos-Diaz, C-
dc.contributor.wosstandardWOS:Jimenez-Monzon, R-
dc.contributor.wosstandardWOS:Diaz-Chico, N-
dc.contributor.wosstandardWOS:Diaz-Chico, JC-
dc.contributor.wosstandardWOS:Fernandez-Perez, L-
dc.date.coverdateJulio 2012en_US
dc.identifier.supplement-;20507;-;-;-;1996;2167-
dc.identifier.supplement-;20507;-;-;-;1996;2167-
dc.identifier.supplement-;20507;-;-;-;1996;2167-
dc.identifier.ulpgcSíen_US
dc.contributor.buulpgcBU-MEDen_US
dc.description.sjr0,535
dc.description.sjrqQ2
dc.description.esciESCI
item.grantfulltextopen-
item.fulltextCon texto completo-
crisitem.author.deptGIR IUIBS: Farmacología Molecular y Traslacional-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Clínicas-
crisitem.author.deptGIR IUIBS: Bioquímica-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Bioquímica y Biología Molecular, Fisiología, Genética e Inmunología-
crisitem.author.deptGIR IUIBS: Bioquímica-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Bioquímica y Biología Molecular, Fisiología, Genética e Inmunología-
crisitem.author.deptGIR IUIBS: Farmacología Molecular y Traslacional-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Clínicas-
crisitem.author.orcid0000-0003-0488-6307-
crisitem.author.orcid0000-0003-4355-5682-
crisitem.author.orcid0000-0002-0944-990X-
crisitem.author.orcid0000-0002-0944-990X-
crisitem.author.orcid0000-0001-7802-465X-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameDe Mirecki Garrido, Mercedes-
crisitem.author.fullNameGuerra Hernández, Carlos Borja-
crisitem.author.fullNameDíaz Chico, Juan Carlos-
crisitem.author.fullNameDíaz Chico, Juan Carlos-
crisitem.author.fullNameFernández Pérez, Leandro Francisco-
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