Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/16731
Title: Safety assessment of plant food supplements (PFS)
Authors: van den Berg, Suzanne
Serra-Majem, Lluis 
Coppens, Patrick
Rietjens,Ivonne
UNESCO Clasification: 3206 Ciencias de la nutrición
Keywords: St-Johns-Wort
Toxicological Concern Ttc
Dna-Adducts
Aristolochic Acid
Risk-Assessment
Mouse-Liver
Kava
Rat
Tea
1'-Hydroxyestragole
Issue Date: 2011
Journal: Food and Function 
Abstract: Botanicals and botanical preparations, including plant food supplements (PFS), are widely used in Western diets. The growing use of PFS is accompanied by an increasing concern because the safety of these PFS is not generally assessed before they enter the market. Regulatory bodies have become more aware of this and are increasing their efforts to ensure the safety of PFS. The present review describes an overview of the general framework for the safety assessment of PFS, focusing on the different approaches currently in use to assess the safety of botanicals and/or botanical compounds, including their history of safe use, the tiered approach proposed by the European Food Safety Authority (EFSA), the Threshold of Toxicological Concern (TTC) and the...
Botanicals and botanical preparations, including plant food supplements (PFS), are widely used in Western diets. The growing use of PFS is accompanied by an increasing concern because the safety of these PFS is not generally assessed before they enter the market. Regulatory bodies have become more aware of this and are increasing their efforts to ensure the safety of PFS. The present review describes an overview of the general framework for the safety assessment of PFS, focusing on the different approaches currently in use to assess the safety of botanicals and/or botanical compounds, including their history of safe use, the tiered approach proposed by the European Food Safety Authority (EFSA), the Threshold of Toxicological Concern (TTC) and the...
URI: http://hdl.handle.net/10553/16731
ISSN: 2042-6496
DOI: 10.1039/c1fo10067j
Source: Food & Function [ISSN 2042-6496)], 2011, v. 2 (12), p. 760-768
Rights: by-nc-nd
Appears in Collections:Reseña
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