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http://hdl.handle.net/10553/113851
Title: | Adopting a High-Polyphenolic Diet Is Associated with an Improved Glucose Profile: Prospective Analysis within the PREDIMED-Plus Trial | Authors: | Tresserra-Rimbau, Anna Castro-Barquero, Sara Becerra-Tomás, Nerea Babio, Nancy Martínez-González, Miguel Ángel Corella, Dolores Fitó, Montserrat Romaguera, Dora Vioque, Jesús Alonso-Gomez, Angel M. Wärnberg, Julia Martínez, José Alfredo Serra Majem, Luis Estruch, Ramon Tinahones, Francisco J. Lapetra, José Pintó, Xavier Tur, Josep A. López-Miranda, José Cano-Ibáñez, Naomi Delgado-Rodríguez, Miguel Matía-Martín, Pilar Daimiel, Lidia Sánchez, Vicente Martín Vidal, Josep Vázquez, Clotilde Ros, Emili Basterra, Francisco Javier de la Puente, María Fernández Asensio, Eva M. Castañer, Olga Bullón-Vela, Vanessa Tojal-Sierra, Lucas Gómez-Gracia, Enrique Cases-Pérez, Eugenio Konieczna, Jadwiga García-Ríos, Antonio Casañas-Quintana, Tamara Bernal-Lopez, María Rosa Santos-Lozano, José Manuel Esteve-Luque, Virginia Bouzas, Cristina Vázquez-Ruiz, Zenaida Palau-Galindo, Antoni Barragan, Rocio Grau, Mercè López Razquín, Cristina Goicolea-Güemez, Leire Toledo, Estefanía Vergaz, Manel Vila Lamuela-Raventós, Rosa M. Salas-Salvadó, Jordi |
UNESCO Clasification: | 32 Ciencias médicas 3206 Ciencias de la nutrición |
Keywords: | Antioxidants Flavonoids Glucose Glycosylated Hemoglobin Hba1C, et al |
Issue Date: | 2022 | Project: | Efecto de la dieta mediterránea hopocalórica y promoción de la actividad física en prevención primaria cardiovascular.Estudio piloto sobre marcadores intermedios. Efecto de Una Pérdida de Peso Con Dieta Mediterránea Hipocalórica y Promoción de la Actividad Física en la Prevención Primaria Cardiovascular Efecto de una intervención intensiva de pérdida de peso con dieta Mediterránea hipocalórica, actividad física y tratamiento conductual sobre la prevención primaria cardiovascular: ensayo PREDIMED-Plus |
Journal: | Antioxidants | Abstract: | Previous studies suggested that dietary polyphenols could reduce the incidence and complications of type-2 diabetes (T2D); although the evidence is still limited and inconsistent. This work analyzes whether changing to a diet with a higher polyphenolic content is associated with an improved glucose profile. At baseline, and at 1 year of follow-up visits, 5921 participants (mean age 65.0 ± 4.9, 48.2% women) who had overweight/obesity and metabolic syndrome filled out a vali-dated 143-item semi-quantitative food frequency questionnaire (FFQ), from which polyphenol intakes were calculated. Energy-adjusted total polyphenols and subclasses were categorized in tertiles of changes. Linear mixed-effect models with random intercepts (the recruitment centers) were used to assess associations between changes in polyphenol subclasses intake and 1-year plasma glucose or glycosylated hemoglobin (HbA1c) levels. Increments in total polyphenol intake and some classes were inversely associated with better glucose levels and HbA1c after one year of follow-up. These associations were modified when the analyses were run considering diabetes status separately. To our knowledge, this is the first study to assess the relationship between changes in the intake of all polyphenolic groups and T2D-related parameters in a senior population with T2D or at high-risk of developing T2D. | URI: | http://hdl.handle.net/10553/113851 | ISSN: | 2076-3921 | DOI: | 10.3390/antiox11020316 | Source: | Antioxidants[EISSN 2076-3921],v. 11 (2), (Febrero 2022) |
Appears in Collections: | Artículos |
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