|Title:||The complete picture of changing pediatric inflammatory bowel disease incidence in Spain in 25years (1985-2009): The EXPERIENCE registry||Authors:||Martín-de-Carpi, J.
Martínez-Gómez, M. J.
Navas-López, V. M.
Serrano Sánchez, José Antonio
Peña Quintana, Luis
de, R. G.
Gutiérrez Cabrera, Carlos Javier
Collado Sánchez, Cayetano
Burriel, J. I.
Balboa, M. J.
Hernández Castellano, Lorenzo Enrique
López, M. A.
Juste de Santa Ana, Candelaria
Eizaguirre, F. J.
Bartolomé, J. M.
Blanca, J. A.
Henríquez Sánchez, Patricia
Fernández Rodríguez, Antonio Jesús
|UNESCO Clasification:||320503 Gastroenterología||Keywords:||Crohn's disease
Pediatric inflammatory bowel disease, et al
|Issue Date:||2014||Journal:||Journal of Crohn's and Colitis||Abstract:||Objectives: A growing incidence of pediatric IBD (PIBD) in southern Europe has been recently reported. The SPIRIT registry (1996-2009) confirmed these tendencies in Spain. Our aim is to obtain data from 1985 to 1995 and describe the complete picture of PIBD presentation changes in Spain in the last 25. years. Methods: A retrospective survey of incident PIBD in the period 1985-1995 was performed. Patients' data were obtained from the hospitals' databases and compared with the published data from the 1996 to 2009 period. Seventy-eight IBD reference centers took part in this survey. Results: Data from 495 patients were obtained: 278 CD (56.2%), 198 UC (40%), and 19 IBDU (3.8%); 51.7% were female, with higher predominance both in UC (58.6%) and in IBDU (57.9%), but not in CD (46.4%). Median (IQR) age at diagnosis was 12.9 (10.0-15.7) years, with significant differences among IBD subtypes: CD: 13.1 (10.8-16.0) vs UC: 12.4 (9.4-15.1) vs IBDU: 7.5 (3.0-13.0) (p ≤ 0.001). These results are significantly different to the ones in the SPIRIT registry, with a higher proportion of IBDU, younger age and male predominance. The data from both periods taken together give a complete picture of a 25-year period. An annual increase of incident patients was observed, with a ten-fold increase over this period. Conclusion: These data extend the epidemiological trends to a full 25-year period (1985-2009). PIBD incidence in Spain has experienced a sixteen-fold increase. The IBD subtype, localization of the affected segment, age- and sex distribution observed are in accordance with our previously published ones of 1996-2009.||URI:||http://hdl.handle.net/10553/108151||ISSN:||1873-9946||DOI:||10.1016/j.crohns.2014.01.005||Source:||Journal of Crohn's and Colitis [ISSN 1873-9946], v. 8(8), p. 763-9|
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