Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/108151
Title: The complete picture of changing pediatric inflammatory bowel disease incidence in Spain in 25years (1985-2009): The EXPERIENCE registry
Authors: Martín-de-Carpi, J.
Rodríguez, A.
Ramos, E.
Jiménez, S.
Martínez-Gómez, M. J.
Medina, E.
Navas-López, V. M.
Serrano Sánchez, José Antonio 
Ricart, E.
Sánchez-Valverde, F.
Peña Quintana, Luis 
de, R. G.
Segarra, O.
Suárez, L.
Gutiérrez Cabrera, Carlos Javier 
Pavón, P.
Barreiro-de-Acosta, M.
Collado Sánchez, Cayetano 
Burriel, J. I.
Ros, I.
Balboa, M. J.
Guallarte, P.
Chaparro, M.
Carpio, D.
Rosell, A.
Torres, R.
Iglesias, C.
Montraveta, M.
Pereda, A.
Hernández Castellano, Lorenzo Enrique 
Armas, H.
Echarri, A.
Barrio, J.
Ortigosa, L.
Manuel, J.
López, M. A.
Peñalva, M.
Juste de Santa Ana, Candelaria 
Martín, M.
Galicia, G.
Eizaguirre, F. J.
Simó, R.
Bartolomé, J. M.
Rodríguez, C.
García, Z.
Barrio, A.
Manrique, O.
García, R.
Ochoa, C.
Masiques, L.
Roca, A.
Blanco, M.
Botella, B.
Rodríguez, A.
Blanca, J. A.
Ubalde, E.
Salcedo, E.
Martín, B.
Vázquez, R.
Carnicer, J.
Henríquez Sánchez, Patricia 
Llorens, E.
Perez-Moneo, B.
Pociello, N.
Fernández Rodríguez, Antonio Jesús 
Torrecillas, J.
Lucendo, A.
Maroto, N.
Pich, M.
UNESCO Clasification: 320503 Gastroenterología
Keywords: Crohn's disease
EXPERIENCE registry
IBD unclassified
Incidence
Pediatric inflammatory bowel disease, et al
Issue Date: 2014
Journal: Journal of Crohn's and Colitis 
Abstract: Objectives: A growing incidence of pediatric IBD (PIBD) in southern Europe has been recently reported. The SPIRIT registry (1996-2009) confirmed these tendencies in Spain. Our aim is to obtain data from 1985 to 1995 and describe the complete picture of PIBD presentation changes in Spain in the last 25. years. Methods: A retrospective survey of incident PIBD in the period 1985-1995 was performed. Patients' data were obtained from the hospitals' databases and compared with the published data from the 1996 to 2009 period. Seventy-eight IBD reference centers took part in this survey. Results: Data from 495 patients were obtained: 278 CD (56.2%), 198 UC (40%), and 19 IBDU (3.8%); 51.7% were female, with higher predominance both in UC (58.6%) and in IBDU (57.9%), but not in CD (46.4%). Median (IQR) age at diagnosis was 12.9 (10.0-15.7) years, with significant differences among IBD subtypes: CD: 13.1 (10.8-16.0) vs UC: 12.4 (9.4-15.1) vs IBDU: 7.5 (3.0-13.0) (p ≤ 0.001). These results are significantly different to the ones in the SPIRIT registry, with a higher proportion of IBDU, younger age and male predominance. The data from both periods taken together give a complete picture of a 25-year period. An annual increase of incident patients was observed, with a ten-fold increase over this period. Conclusion: These data extend the epidemiological trends to a full 25-year period (1985-2009). PIBD incidence in Spain has experienced a sixteen-fold increase. The IBD subtype, localization of the affected segment, age- and sex distribution observed are in accordance with our previously published ones of 1996-2009.
URI: http://hdl.handle.net/10553/108151
ISSN: 1873-9946
DOI: 10.1016/j.crohns.2014.01.005
Source: Journal of Crohn's and Colitis [ISSN 1873-9946], v. 8(8), p. 763-9
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