Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/44504
Título: Individualized Therapy with Ranibizumab in Wet Age-Related Macular Degeneration
Autores/as: García-Layana, Alfredo
Figueroa, Marta S.
Arias, Luis
Araiz, Javier
Ruiz-Moreno, José María
García-Arumí, José
Gómez-Ulla, Francisco
López-Gálvez, María Isabel
Cabrera-López, Francisco 
García-Campos, José Manuel
Monés, Jordi
Cervera, Enrique
Armadá, Felix
Gallego-Pinazo, Roberto
Clasificación UNESCO: 320109 Oftalmología
Fecha de publicación: 2015
Editor/a: 2090-004X
Publicación seriada: Journal of Ophthalmology 
Resumen: Individualized treatment regimens may reduce patient burden with satisfactory patient outcomes in neovascular age-related macular degeneration. Intravitreal anti-VEGF drugs are the current gold standard. Fixed monthly injections offer the best visual outcome but this regimen is not commonly followed outside clinical trials. A PRN regimen requires monthly visits where the patient is treated in the presence of signs of lesion activity. Therefore, an early detection of reactivation of the disease with immediate retreatment is crucial to prevent visual acuity loss. Several trials suggest that “treat and extend” and other proactive regimens provide a reasonable approach. The rationale of the proactive regimens is to perform treatment anticipating relapses or recurrences and therefore avoid drops in vision while individualizing patient followup. Treat and extend study results in significant direct medical cost savings from fewer treatments and office visits compared to monthly treatment. Current data suggest that, for one year, PRN is less expensive, but treat and extend regimen would likely be less expensive for subsequent years. Once a patient is not a candidate to continue with treatment, he/she should be sent to an outpatient unit with adequate resources to follow nAMD patients in order to reduce the burden of specialized ophthalmologist services.
URI: http://hdl.handle.net/10553/44504
ISSN: 2090-004X
DOI: 10.1155/2015/412903
Fuente: Journal of Ophthalmology [ISSN 2090-004X], v. 2015 (412903)
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