Goat colostrum-derived exosomes: the shocking secrets of cellular communication

Abstract

Colostrum is described as the first secretion of the mammary gland after parturition which contains a complex mixture of bioactive component. After gradual changes colostrum become to mature milk. The development of new laboratory techniques has allowed to know in deep components that are in low abundance or those which has small size. Exosomes are small membranous vesicles (20-300 nm in diameter) found in different biological fluids, such as colostrum and milk. Cell-to cell communication is the most known function, but exosomes are also noted because of their use in human cancer therapy. Furthermore, the role of colostrum-derived exosomes in immunological processes has been reported. The study of the whole transcriptome profile of goat colostrumderived exosomes provides very interesting information about the potential roles of the genes carried by these still not well known extravesicles. To study in deep the cargo molecules contained in the goat colostrum and milk derived-exosomes is crucial to elucidate the shocking secret of these small vesicles.