Hígado graso no alcoholico y obesidad infanto-juvenil

Abstract

El hígado graso no alcohólico (NAFLD) se define como la acumulación macrovesicular de grasa superior al 5% de los hepatocitos y se engloba en este término la esteatosis simple, la esteatohepatitis no alcohólica (NASH) con inflamación, varios grados de fibrosis o ambas y la cirrosis. En la actualidad no existe consenso sobre el tratamiento en NAFLD/NASH. Básicamente consistirá en evitar el consumo de alcohol, reducir la grasa hepática y el estrés oxidativo, para prevenir el desarrollo de fibrosis, que podría conllevar cirrosis e hipertensión portal (AU)

Non-alcoholic fatty liver disease (NAFLD) is defined as the macrovesicular fat accumulation greater than 5% of the hepatocytes and this term includes the simple steatosis, non-alcoholic steatoheatitis (NAS with inflammation, several grades of fibrosis or both and cirrosis. Currently, there is no consensus on the treatment of NAFLD/NASH. Basically, it would consist in avoiding alcohol consumption, reducing it would consist in avoiding alcohol consumption, reducing liver fat and oxidative stress, to prevent the development of fibrosis, that could lead to cirrhosis and portal hypertension (AU)