|Title:||Progress in farm animal proteomics: The contribution of combinatorial peptide ligand libraries||Authors:||Boschetti, Egisto
Hernández Castellano, Lorenzo Enrique
Righetti, Pier Giorgio
|UNESCO Clasification:||3104 Producción Animal||Keywords:||Combinatorial peptide ligand libraries
|Issue Date:||2019||Journal:||Journal of Proteomics||Abstract:||The present review covers proteomics discoveries in farm animals using combinatorial peptide ligand libraries (CPLLs). These libraries enhance the identification of low-abundance proteins by compressing the dynamic range of the protein concentration. This technology can be applied in multiple biological fluids, such as plasma or serum, follicular and cerebrospinal fluids, urine, saliva, tears seminal fluid, milk whey and even lymph. The discovery of low-abundance proteins contributes to the continuous monitoring for animal pathologies, which allows early treatment and disease prevention. Additionally, evidencing rare proteins in animal products used for human consumption can help in assessing their nutritional properties and their positive or negative effects on human health.||URI:||http://hdl.handle.net/10553/77924||ISSN:||1874-3919||DOI:||10.1016/j.jprot.2019.02.005||Source:||Journal of Proteomics [ISSN 1874-3919], n. 197, p. 1-13|
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