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Title: Progress in farm animal proteomics: The contribution of combinatorial peptide ligand libraries
Authors: Boschetti, Egisto
Hernández Castellano, Lorenzo Enrique 
Righetti, Pier Giorgio
UNESCO Clasification: 3104 Producción Animal
Keywords: Combinatorial peptide ligand libraries
Low-abundance proteins
Animal health
Animal proteomes
Issue Date: 2019
Journal: Journal of Proteomics 
Abstract: The present review covers proteomics discoveries in farm animals using combinatorial peptide ligand libraries (CPLLs). These libraries enhance the identification of low-abundance proteins by compressing the dynamic range of the protein concentration. This technology can be applied in multiple biological fluids, such as plasma or serum, follicular and cerebrospinal fluids, urine, saliva, tears seminal fluid, milk whey and even lymph. The discovery of low-abundance proteins contributes to the continuous monitoring for animal pathologies, which allows early treatment and disease prevention. Additionally, evidencing rare proteins in animal products used for human consumption can help in assessing their nutritional properties and their positive or negative effects on human health.
ISSN: 1874-3919
DOI: 10.1016/j.jprot.2019.02.005
Source: Journal of Proteomics [ISSN 1874-3919], n. 197, p. 1-13
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