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Title: In Vivo and In Vitro Models of Diabetes: A Focus on Pregnancy
Authors: Lilao Garzón, Joaquín 
Valverde Tercedor, María Del Carmen 
Muñoz Descalzo, Silvia 
Brito Casillas, Yeray 
Wägner, Anna Maria Claudia 
UNESCO Clasification: 32 Ciencias médicas
320502 Endocrinología
Keywords: Animal model
Embryo culture
Gestational diabetes, et al
Issue Date: 2020
Journal: Advances in Experimental Medicine and Biology 
Abstract: Diabetes in pregnancy is associated with an increased risk of poor outcomes, both for the mother and her offspring. Although clinical and epidemiological studies are invaluable to assess these outcomes and the effectiveness of potential treatments, there are certain ethical and practical limitations to what can be assessed in human studies. Thus, both in vivo and in vitro models can aid us in the understanding of the mechanisms behind these complications and, in the long run, towards their prevention and treatment. This review summarizes the existing animal and cell models used to mimic diabetes, with a specific focus on the intrauterine environment.
ISBN: 978-3-030-51088-6
ISSN: 0065-2598
DOI: 10.1007/5584_2020_536
Source: Advances in Experimental Medicine and Biology [0065-2598], n. 1307, p. 553-576
Appears in Collections:Artículos
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