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Title: In-laboratory removal of femoral sheath following protamine administration in patients having intracoronary stent implantation
Authors: Pan, Manuel
Suárez de Lezo, José
Medina, Alfonso
Romero, Miguel
Hernández, Enrique
Segura, José
Melián, Francisco
Wangüemert, Fernando
Landin, Manuel
Benítez, Fernando
Amat, Manuel
Velasco, Francisco
Torres, Antonio
UNESCO Clasification: 320501 Cardiología
Keywords: Venous Bypass Grafts
Coronary Angioplasty
Ultrasound Guidance
Anticoagulation, et al
Issue Date: 1997
Journal: The American journal of cardiology 
Abstract: After coronary stent implantation, antithrombotic therapy is required; however, the specific drug combination to use is still under debate.(1) The ideal regimen should avoid subacute stent thrombosis and hemorrhagic complications and allow an early hospital discharge. The purpose of this study is the evaluation of the safety and efficiency of neutralizing circulating heparin with protamine administration immediately after coronary stent implantation. We hypothesized that the in-laboratory removal of the femoral sheath could reduce groin complications and would shorten the postprocedural period of bed rest and hospital stay after stent implantation. To test this hypothesis, our study compares, in a randomized way, the hospital course of patients with early sheath removal after protamine administration with those in which the femoral sheath was removed after the complete spontaneous disappearance of heparin activity.
ISSN: 0002-9149
DOI: 10.1016/s0002-9149(97)00676-0
Source: The American journal of cardiology [ISSN 0002-9149], v. 80 (10), p. 1336-8, (Noviembre 1997)
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