Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/76578
Title: Serial Angiographic Observations After Successful Directional Coronary Atherectomy
Authors: Medina, Alfonso
Suárez de Lezo, José
Hernández, Enrique
Pan, Manuel
Ortega, José
Romero, Miguel
Melián, Francisco
Pavlovic, Djordje
Marrero, José
Cabrera, José A.
UNESCO Clasification: 320501 Cardiología
321307 Cirugía del corazón
Keywords: Angioplasty
Restenosis
Issue Date: 1993
Journal: The American heart journal 
Abstract: This study focuses on the early and late angiographic evolution observed in 82 patients with coronary artery disease who were successfully treated by directional coronary atherectomy (DCA) without adjunctive balloon angioplasty. Qualitative inspections and quantitative measurements were obtained from a selected angled-view projection in the following conditions: (1) before treatment; (2) immediately after treatment; (3) the day after atherectomy; (4) 1 month after; and (5) 6 months after. The appearance of the treated segment 24 hours after the procedure did not differ in 79 patients from that observed immediately after DCA; silent total occlusion occurred in two patients, and one had an aneurysm at the site of resection (all three patients were excluded from the analysis). At the 1-month study restenosis developed in 3 (3.6%) patients; the remaining 76 had identical appearances, with no evidence of renarrowing of the lumen. However, from 1 to 6 months after the procedure restenosis developed in 35 of the remaining 76 (46%) patients, and 41 patients were free of restenosis and symptoms. These findings, which show that early elastic recoil does not occur after successful DCA, are different from the changes observed after balloon angioplasty. At the 1-month observation restenosis is an infrequent but possible phenomenon (3.8%). From this point the healing of the arterial wall leads to no or mild renarrowing (late success); an exaggerated proliferative response produces restenosis.
URI: http://hdl.handle.net/10553/76578
ISSN: 0002-8703
DOI: 10.1016/0002-8703(93)90987-K
Source: American Heart Journal[ISSN 0002-8703],v. 125 (5), p. 1217-1221, (Mayo 1993)
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