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Title: Serological Markers In Hepatitis-B - Atypical Patterns Detected At Hospital-Insular, Gran-Canaria
Other Titles: Serum hepatitis B markers: atypical patterns detected at the Hospital Insular de Gran Canaria
Authors: Santana, O. E.
Francés, A.
Sierra, A.
Hernández, J.
Martín Sánchez, A. M.
UNESCO Clasification: 320103 Microbiología clínica
Keywords: HBV
Serological Markers
Issue Date: 1995
Journal: Revista clínica española (Ed. impresa) 
Abstract: Two atypical serological markers of hepatitis B virus (HBV) infection were detected in 19 patients during a 18-month period study. Pattern 1 (10 patients) was consistent with HBV-2 infection. Reactivity of HbsAG was confirmed by neutralization tests; the absence of other markers was also verified, included anti-HBclgM. Three of the patients were classified in high risk groups and seven in the low risk groups for hepatitis B; in none of them was co-infection with hepatitis A virus (HAV) detected. Pattern 2 (9 patients) was characterized by the detection of HBsAg and HBeAg and the absence of other hepatitis B markers. Six of these patients were HIV-positive patients and had increased and persistent levels (for longer than 12 weeks) of these markers. In the three remaining patients (with no underlying immunological disorders) there was a loss of these markers within a variable time (2 days to 16 weeks). Nevertheless, DNA-VHB was detected in one of these serum samples once all markers of virus B had disappeared.
ISSN: 0014-2565
Source: Revista clínica española [ISSN 0014-2565], v. 195 (10), p. 674-677, (Octubre 1995)
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