Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/76426
Campo DC Valoridioma
dc.contributor.authorHenríquez Hernández, Luis Albertoen_US
dc.contributor.authorOrtiz-Andrelluchi, A.en_US
dc.contributor.authorÁlvarez-Pérez, J.en_US
dc.contributor.authorAcosta Dacal, Andrea Carolinaen_US
dc.contributor.authorZumbado Peña, Manuel Luisen_US
dc.contributor.authorMartínez-González, M. A.en_US
dc.contributor.authorDomínguez Boada, Luis Maríaen_US
dc.contributor.authorSalas-Salvadó, J.en_US
dc.contributor.authorPérez Luzardo, Octavio Luisen_US
dc.contributor.authorSerra Majem, Luisen_US
dc.date.accessioned2020-12-09T09:37:22Z-
dc.date.available2020-12-09T09:37:22Z-
dc.date.issued2021en_US
dc.identifier.issn0048-9697en_US
dc.identifier.otherScopus-
dc.identifier.otherWoS-
dc.identifier.urihttp://hdl.handle.net/10553/76426-
dc.description.abstractThe population of the Canary Islands has been exposed to high levels of persistent organic pollutants (POPs). Biomonitoring studies are essential to know the temporal trend in residue levels, particularly of substances banned decades ago. The purpose of this study was to analyze the distribution of plasma concentrations of 59 POPs in 175 participants from the PREDIMED-Plus trial (2014–2016), and to compare them with the distribution of these POPs in 343 participants in the PREDIMED trial (2006–2009). All participants had metabolic syndrome. No difference in the distribution of age, gender or BMI was observed between trials. POPs were determined by gas chromatography–mass spectrometry. Density plots —POP Geoffrey Rose curves— were used to represent the full population distribution of each compound. Three out of 59 POPs were detected and quantified in ≥95% of the samples (p,p′-DDE, median = 694.7 ng/g lipid; HCB, median = 57.0 ng/g lipid; and β-HCH, median = 75.7 ng/g lipid). PCB congeners 138, 153 and 180 were detected in 64.6, 40.0 and 88.0% of the samples. Females showed highest concentrations of organochlorine pesticides and those subjects who lost ˃ 5 kg showed significant higher plasma concentrations of POPs. In a range of 6–14 years, plasma concentrations of POPs decreased 3.3–21.6 fold, being notable the decrease of 28.7-fold observed for HCB among women. Despite this sharp decline, levels of POPs are still higher than those reported in other regions, since one third of the subjects included in the present report had high concentration of more than three pollutants. Continuous biomonitoring studies are required to know the evolution of the levels of residues and to evaluate the effectiveness of environmental policies.en_US
dc.languageengen_US
dc.relation.ispartofScience of the Total Environmenten_US
dc.sourceScience of the Total Environment [ISSN 0048-9697], n. 758, 143637en_US
dc.subject3214 Toxicologíaen_US
dc.subject3212 Salud públicaen_US
dc.subject.otherHuman Biomonitoringen_US
dc.subject.otherOrganochlorine Pesticidesen_US
dc.subject.otherPolychlorinated Biphenylsen_US
dc.titleHuman biomonitoring of persistent organic pollutants in elderly people from the Canary Islands (Spain): A temporal trend analysis from the PREDIMED and PREDIMED-Plus cohortsen_US
dc.typeinfo:eu-repo/semantics/Articleen_US
dc.typeArticleen_US
dc.identifier.doi10.1016/j.scitotenv.2020.143637en_US
dc.identifier.scopus85096855972-
dc.identifier.isi000605623800050-
dc.contributor.authorscopusid15829708200-
dc.contributor.authorscopusid57220090761-
dc.contributor.authorscopusid24586741900-
dc.contributor.authorscopusid56096659300-
dc.contributor.authorscopusid6603459604-
dc.contributor.authorscopusid7004290629-
dc.contributor.authorscopusid6603916807-
dc.contributor.authorscopusid7003357665-
dc.contributor.authorscopusid6507534124-
dc.contributor.authorscopusid35596972100-
dc.identifier.eissn1879-1026-
dc.relation.volume758en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.contributor.daisngid36375247-
dc.contributor.daisngid12724434-
dc.contributor.daisngid5095095-
dc.contributor.daisngid42671618-
dc.contributor.daisngid30415411-
dc.contributor.daisngid14474-
dc.contributor.daisngid1656886-
dc.contributor.daisngid25605-
dc.contributor.daisngid42520810-
dc.contributor.daisngid28836-
dc.description.numberofpages10en_US
dc.utils.revisionen_US
dc.contributor.wosstandardWOS:Henriquez-Hernandez, LA-
dc.contributor.wosstandardWOS:Ortiz-Andrelluchi, A-
dc.contributor.wosstandardWOS:Alvarez-Perez, J-
dc.contributor.wosstandardWOS:Acosta-Dacal, A-
dc.contributor.wosstandardWOS:Zumbado, M-
dc.contributor.wosstandardWOS:Martinez-Gonzalez, MA-
dc.contributor.wosstandardWOS:Boada, LD-
dc.contributor.wosstandardWOS:Salas-Salvado, J-
dc.contributor.wosstandardWOS:Luzardo, OP-
dc.contributor.wosstandardWOS:Serra-Majem, L-
dc.date.coverdateMarzo 2021en_US
dc.identifier.ulpgcen_US
dc.contributor.buulpgcBU-MEDen_US
dc.description.sjr1,806
dc.description.jcr10,753
dc.description.sjrqQ1
dc.description.jcrqQ1
dc.description.scieSCIE
dc.description.miaricds11,0
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.author.deptGIR IUIBS: Medio Ambiente y Salud-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Clínicas-
crisitem.author.deptGIR IUIBS: Nutrición-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptGIR IUIBS: Medio Ambiente y Salud-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptGIR IUIBS: Medio Ambiente y Salud-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Clínicas-
crisitem.author.deptGIR IUIBS: Medio Ambiente y Salud-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Clínicas-
crisitem.author.deptGIR IUIBS: Medio Ambiente y Salud-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Clínicas-
crisitem.author.deptGIR IUIBS: Nutrición-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Clínicas-
crisitem.author.orcid0000-0003-3237-0316-
crisitem.author.orcid0000-0001-5726-3731-
crisitem.author.orcid0000-0002-1272-0545-
crisitem.author.orcid0000-0002-1534-7758-
crisitem.author.orcid0000-0002-0195-4565-
crisitem.author.orcid0000-0002-4153-3028-
crisitem.author.orcid0000-0002-9658-9061-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameHenríquez Hernández, Luis Alberto-
crisitem.author.fullNameÁlvarez Pérez,Jacqueline-
crisitem.author.fullNameAcosta Dacal, Andrea Carolina-
crisitem.author.fullNameZumbado Peña, Manuel Luis-
crisitem.author.fullNameDomínguez Boada, Luis María-
crisitem.author.fullNamePérez Luzardo, Octavio Luis-
crisitem.author.fullNameSerra Majem, Luis-
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