Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/75831
Title: All-optical phase modulation for integrated interferometric biosensors
Authors: Dante, Stefania
Duval, Daphné
Sepúlveda, Borja
González-Guerrero, Ana Belen
Sendra, José Ramón 
Lechuga, Laura M.
UNESCO Clasification: 3307 Tecnología electrónica
Keywords: Optical sensors
Phase modulation
Interferometry
Biological sensing
Issue Date: 2012
Journal: Optics Express 
Abstract: We present the theoretical and the experimental implementation of an all-optical phase modulation system in integrated Mach-Zehnder Interferometers to solve the drawbacks related to the periodic nature of the interferometric signal. Sensor phase is tuned by modulating the emission wavelength of low-cost commercial laser diodes by changing their output power. FFT deconvolution of the signal allows for direct phase readout, immune to sensitivity variations and to light intensity fluctuations. This simple phase modulation scheme increases the signal-to-noise ratio of the measurements in one order of magnitude, rendering in a sensor with a detection limit of 1.9·10-7 RIU. The viability of the all-optical modulation approach is demonstrated with an immunoassay detection as a biosensing proof of concept.
URI: http://hdl.handle.net/10553/75831
DOI: 10.1364/OE.20.007195
Source: Optics Express[EISSN 1094-4087],v. 20 (7), p. 7195-7205, (Marzo 2012)
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