1. accedaCRIS
  2. Publicaciones
  3. Artículos
Please use this identifier to cite or link to this item: https://accedacris.ulpgc.es/handle/10553/75367
DC FieldValueLanguage
dc.contributor.authorTena Pérez, Víctoren_US
dc.contributor.authorApaza Ticona, Luisen_US
dc.contributor.authorCabanillas, Alfredo H.en_US
dc.contributor.authorMaderuelo Corral, Santiagoen_US
dc.contributor.authorRosero Valencia, Diego Fernandoen_US
dc.contributor.authorMartel Quintana, Anteraen_US
dc.contributor.authorOrtega Domenech, Montserraten_US
dc.contributor.authorRumbero Sánchez, Ángelen_US
dc.date.accessioned2020-11-11T09:21:14Z-
dc.date.available2020-11-11T09:21:14Z-
dc.date.issued2021en_US
dc.identifier.issn1478-6419en_US
dc.identifier.otherScopus-
dc.identifier.urihttps://accedacris.ulpgc.es/handle/10553/75367-
dc.description.abstractActivity-guided fractionations from the freshwater cyanobacterium Nodularia harveyana led to the isolation of two monogalactosyldiacylglycerols (MGDG), two digalactosyldiacylglycerols (DGDG), two monoglucosyldiacylglycerols (MGlcDG) and 1-(O-hexose)-3,25-hexacosanediol (HG). Structures were elucidated by a combination of 1D and 2D NMR analysis, HRMS and GC-MS. The potential for inhibition against TNF-α and NF-κB production of these seven compounds was tested in THP-1 cells. All compounds showed activity, but compound 7 showed higher inhibitory activity of TNF-α and NF-κB, with IC50 of 4.88 ± 0.13 and 3.64 ± 0.45 μM, respectively.en_US
dc.languageengen_US
dc.relation.ispartofNatural Product Researchen_US
dc.sourceNatural Product Research [ISSN 1478-6419], v. 35(24), p. 6204-6209en_US
dc.subject230690 Química de productos naturales orgánicosen_US
dc.subject.otherAnti-Inflammatoryen_US
dc.subject.otherCyanobacteriumen_US
dc.subject.otherGlycolipidsen_US
dc.subject.otherNf-Κben_US
dc.subject.otherNodularia Harveyanaen_US
dc.subject.otherTnf-Αen_US
dc.titleAnti-inflammatory activity of glycolipids isolated from cyanobacterium Nodularia harveyanaen_US
dc.typeinfo:eu-repo/semantics/Articleen_US
dc.typeArticleen_US
dc.identifier.doi10.1080/14786419.2020.1837808en_US
dc.identifier.scopus85094610118-
dc.contributor.authorscopusid56072150900-
dc.contributor.authorscopusid55142024800-
dc.contributor.authorscopusid57200917147-
dc.contributor.authorscopusid57200920009-
dc.contributor.authorscopusid57200916252-
dc.contributor.authorscopusid57197486214-
dc.contributor.authorscopusid57200917636-
dc.contributor.authorscopusid57200916894-
dc.identifier.eissn1478-6427-
dc.investigacionCienciasen_US
dc.type2Artículoen_US
dc.description.numberofpages6en_US
dc.utils.revisionSíen_US
dc.identifier.ulpgcSíen_US
dc.contributor.buulpgcBU-BASen_US
dc.description.sjr0,446
dc.description.jcr2,488
dc.description.sjrqQ2
dc.description.jcrqQ3
dc.description.scieSCIE
dc.description.miaricds11,0
item.fulltextSin texto completo-
item.grantfulltextnone-
crisitem.author.deptGIR IOCAG: Oceanografía Biológica y Algología Aplicada-
crisitem.author.deptIU de Oceanografía y Cambio Global-
crisitem.author.orcid0000-0002-7450-0505-
crisitem.author.parentorgIU de Oceanografía y Cambio Global-
crisitem.author.fullNameMartel Quintana,Antera De Jesús-
Appears in Collections:Artículos
Show simple item record

SCOPUSTM   
Citations

6
checked on Mar 30, 2025

WEB OF SCIENCETM
Citations

5
checked on Mar 30, 2025

Page view(s)

94
checked on May 11, 2024

Google ScholarTM

Check

Altmetric


Share


Export metadata


Items in accedaCRIS are protected by copyright, with all rights reserved, unless otherwise indicated.