Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/75055
Title: NADPH-Diaphorase (NOS) is induced in pyramidal neurons of hippocampal slices
Authors: Divac, Ivan
Ramírez González, Juan Andrés 
Ronn, Lars C. B.
Jahnsen, Henrik
Regidor García,José 
UNESCO Clasification: 240703 Morfología celular
Keywords: Nitric-Oxide Synthase
Long-Term Potentiation
Retrograde Messenger
Issue Date: 1993
Journal: NeuroReport 
Abstract: WE found NADPH-diaphorase (presumably identical with nitric oxide synthase) in pyramidal neurones of the hippocampus in slices that stayed in a chamber for 30 min or longer. In some instances parallel slices showed normal membrane properties when studied electrophysiologically. In freshly made slices the pyramidal neurones were not stained. Thus, after induction of the enzyme, the hippocampal pyramidal neurones can synthesize nitric oxide which may serve as a retrograde messenger in long-term potentiation. The enzyme may also play a role in cell loss seen in slices which stayed in a chamber for 9-22 h before fixation.
URI: http://hdl.handle.net/10553/75055
ISSN: 0959-4965
DOI: 10.1097/00001756-199312000-00037
Source: Neuroreport [ISSN 0959-4965], v. 5 (3), p. 325-328, (Diciembre 1993)
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