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Title: Mediterranean alcohol drinking pattern and risk of atrial fibrillation in the PREDIMED study
Authors: Bazal, P.
Aros, F.
Toledo, E.
Gea, A.
Fiol, M.
Salas-Salvado, J.
Corella, D.
Fito, M.
Gomez-Gracia, E.
Lapetra, J.
Serra Majem, Luis 
Pinto, X.
Ros, E.
Martinez-Gonzalez, M. A.
Ruiz-Canela, M.
UNESCO Clasification: 320501 Cardiología
3206 Ciencias de la nutrición
Keywords: Alcohol
Atrial fibrillation
Red wine
Issue Date: 2016
Journal: European Heart Journal 
Conference: Congress of the European-Society-of-Cardiology (ESC) 
Abstract: There is ongoing controversy about the effect of a low to moderate alcohol consumption on atrial fibrillation (AF). Our aim is to assess the association between adherence to a Mediterranean alcohol drinking pattern and AF incidence. Methods and results: A total 6527 out of the 7447 participants in the PREDIMED trial met our inclusion criteria. A validated frequency food questionnaire was used to measure alcohol consumption. Participants were classified as non-drinkers, Mediterranean alcohol drinking pattern (MADP) (10–30 g/d in men and 5–15 g/day in women, preferably red wine consumption with low spirits consumption), low-moderate drinking (<30 g/day men y and < 15 g/day women), and heavy drinking. We performed multivariable Cox regression models to estimate hazard ratios (HR) with 95% confidence intervals (95% CI) of incident AF according to alcohol drinking patterns. After a mean follow up of 4.4 years, 241 new incident AF cases were confirmed. Alcohol consumption was not associated to AF incidence among low-moderate drinkers (HR: 0.96; 95%CI: 0.67–1.37), adherents to MADP (HR: 1.15 95%CI: 0.75–1.75), or heavy drinkers (HR: 0.92; 95%CI: 0.53–1.58), compared with non-drinkers. Conclusions: In a high cardiovascular risk adult population, a Mediterranean alcohol consumption pattern (low to moderate red wine consumption) was not associated with an increased incidence of AF.
ISSN: 0195-668X
Source: European Heart Journal [ISSN 0195-668X], v. 37 sup. 1, p. 1347, Abstract P6441, (Agosto 2016)
Appears in Collections:Actas de congresos
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