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Title: Accelerated partial breast irradiation with interstitial multicatheter brachytherapy after breast-conserving surgery for low-risk early breast cancer
Authors: Rodriguez-Ibarria, Nieves G.
Pinar Sedeño, Ma Beatriz
García, Laura
Cabezón, M. Auxiliadora
Lloret Sáez-Bravo, Marta 
Rey-Baltar, Ma Dolores
Rdguez-Melcón, J. Ignacio
Lara, Pedro C.
UNESCO Clasification: 320101 Oncología
3213 Cirugía
Keywords: Brachytherapy
Breast Cancer
Early Breast Cancer
Partial Breast Irradiation
Issue Date: 2020
Journal: Breast 
Abstract: Patients with low-risk invasive ductal carcinoma treated with breast-conserving surgery (BCS) were included in a multicatheter brachytherapy APBI protocol. The primary endpoint was ipsilateral breast recurrence. Between December 2008–December 2017, 186 low-risk breast cancer patients were treated with APBI using interstitial multicatheter brachytherapy and followed prospectively. At 5-years of follow-up, cumulative local recurrence (LR) and cause-specific survival was 1.1% (95% CI 0.3–1.9) and 98.3% (95% CI 97.3–99.3%) respectively. No grade 3 adverse effects were observed. Postoperative APBI using multicatheter brachytherapy after BCS in early breast cancer patients have excellent rates of local control and survival, without significant toxicity.
ISSN: 0960-9776
DOI: 10.1016/j.breast.2020.04.008
Source: Breast [ISSN 0960-9776], v. 52, p. 45-49, (Agosto 2020)
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