Please use this identifier to cite or link to this item:
http://hdl.handle.net/10553/71941
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Fornell-Perez, Roberto | en_US |
dc.contributor.author | Vivas-Escalona, Valentina | en_US |
dc.contributor.author | Aranda-Sanchez, Joel | en_US |
dc.contributor.author | Gonzalez-Dominguez, M. Carmen | en_US |
dc.contributor.author | Rubio-Garcia, Jano | en_US |
dc.contributor.author | Alemán-Flores, Patricia | en_US |
dc.contributor.author | Lozano-Rodriguez, Alvaro | en_US |
dc.contributor.author | Porcel-de-Peralta, Gabriela | en_US |
dc.contributor.author | Loro Ferrer, Juan Francisco | en_US |
dc.date.accessioned | 2020-05-04T10:56:07Z | - |
dc.date.available | 2020-05-04T10:56:07Z | - |
dc.date.issued | 2020 | en_US |
dc.identifier.issn | 0033-8362 | en_US |
dc.identifier.other | WoS | - |
dc.identifier.uri | http://hdl.handle.net/10553/71941 | - |
dc.description.abstract | Objective: To assess the added value of diffusion-weighted imaging (DWI) to high-resolution T2-weighted sequences (HRT2w) in MRI detection of extramural venous infiltration (EMVI), according to the previous experience of radiologists. Methods: A cross-sectional study of a retrospective database including 1.5 T MRI records from 100 patients with biopsy-proven rectal cancer (2011-2016; 75 male/25 female, average 63 y/o), which included primary staging (54) and post-chemoradiotherapy follow-up MRIs (46). The reference standard was histology of surgical specimens. All cases were individually blindly reviewed by ten radiologists: three specialists in abdominal radiology, three specialized in different areas and four residents. In each case, the presence of EMVI was assessed twice: first, using just HRT2w; second, with DWI added to HRT2w. The results were pooled by experience, analyzing sensitivity, specificity, accuracy (area under ROC curve), likelihood ratios, predictive values and overstaging/understaging. Results Addition of DWI improved diagnostic performance by specialists radiologists, particularly post-chemoradiotherapy (accuracy 0.74-0.84; positive likelihood ratio 3.9-9.1; overstaging 16-8%), less so at primary staging (specificity 76-87.2%; overstaging 21-11%). Non-specialist radiologists also improved, but only at primary staging (accuracy 0.59-0.63). Residents showed small changes, except for notably increased sensitivity in both primary staging (35.7-43%) and post-chemoradiotherapy (41.7-58.3%) staging, at the expense of increased overstaging. Conclusions: The addition of DWI improved the diagnostic performance of EMVI by experienced radiologists, downgrading overstaging, especially in post-chemoradiotherapy follow-up. It resulted in fewer changes for inexperienced radiologists (enhanced primary staging) and residents (increased sensitivity). | en_US |
dc.language | eng | en_US |
dc.relation.ispartof | Radiologia Medica | en_US |
dc.source | Radiologia Medica [ISSN 0033-8362], v. 125, p. 522–530 | en_US |
dc.subject | 320101 Oncología | en_US |
dc.subject | 320111 Radiología | en_US |
dc.subject.other | Vascular Invasion | en_US |
dc.subject.other | Prognostic-Significance | en_US |
dc.subject.other | Chemotherapy | en_US |
dc.subject.other | Metastasis | en_US |
dc.subject.other | Disease | en_US |
dc.subject.other | Magnetic Resonance Imaging | en_US |
dc.subject.other | Rectal Neoplasms | en_US |
dc.subject.other | Diffusion-Weighted Imaging | en_US |
dc.subject.other | Blood Vessels | en_US |
dc.title | Primary and post-chemoradiotherapy MRI detection of extramural venous invasion in rectal cancer: the role of diffusion-weighted imaging | en_US |
dc.type | info:eu-repo/semantics/Article | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1007/s11547-020-01137-7 | en_US |
dc.identifier.isi | 000511074000004 | - |
dc.identifier.eissn | 1826-6983 | - |
dc.investigacion | Ciencias de la Salud | en_US |
dc.type2 | Artículo | en_US |
dc.contributor.daisngid | 34800023 | - |
dc.contributor.daisngid | 31991154 | - |
dc.contributor.daisngid | 31991734 | - |
dc.contributor.daisngid | 34804087 | - |
dc.contributor.daisngid | 11250725 | - |
dc.contributor.daisngid | 6193922 | - |
dc.contributor.daisngid | 6665551 | - |
dc.contributor.daisngid | 32004636 | - |
dc.contributor.daisngid | 29163246 | - |
dc.description.numberofpages | 9 | en_US |
dc.utils.revision | Sí | en_US |
dc.contributor.wosstandard | WOS:Fornell-Perez, R | - |
dc.contributor.wosstandard | WOS:Vivas-Escalona, V | - |
dc.contributor.wosstandard | WOS:Aranda-Sanchez, J | - |
dc.contributor.wosstandard | WOS:Gonzalez-Dominguez, MC | - |
dc.contributor.wosstandard | WOS:Rubio-Garcia, J | - |
dc.contributor.wosstandard | WOS:Aleman-Flores, P | - |
dc.contributor.wosstandard | WOS:Lozano-Rodriguez, A | - |
dc.contributor.wosstandard | WOS:Porcel-de-Peralta, G | - |
dc.contributor.wosstandard | WOS:Loro-Ferrer, JF | - |
dc.date.coverdate | 2020 | en_US |
dc.identifier.ulpgc | Sí | en_US |
dc.contributor.buulpgc | BU-MED | en_US |
dc.description.sjr | 0,581 | |
dc.description.jcr | 3,469 | |
dc.description.sjrq | Q2 | |
dc.description.jcrq | Q2 | |
dc.description.scie | SCIE | |
item.fulltext | Sin texto completo | - |
item.grantfulltext | none | - |
crisitem.author.dept | GIR IUIBS: Bioquímica | - |
crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.dept | Departamento de Ciencias Clínicas | - |
crisitem.author.orcid | 0000-0002-0517-8209 | - |
crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.fullName | Loro Ferrer, Juan Francisco | - |
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