Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/70753
Title: Association Between Lifestyle and Hypertriglyceridemic Waist Phenotype in the PREDIMED-Plus Study
Authors: Fernández-García, José Carlos
Muñoz-Garach, Araceli
Martínez-González, Miguel Ángel
Salas-Salvado, Jordi
Corella, Dolores
Hernáez, Álvaro
Romaguera, Dora
Vioque, Jesús
Alonso-Gómez, Ángel M.
Wärnberg, Julia
Martínez, J. Alfredo
Serra Majem, Lluis 
Estruch, Ramón
Lapetra, José
Pintó, Xavier
Tur, Josep A.
Garcia-Rios, Antonio
García Molina, Laura
Gaforio, José Juan
Matía-Martín, Pilar
Daimiel, Lidia
Martín Sánchez, Vicente
Vidal, Josep
Prieto, Lucia
Ros, Emilio
Goñi, Nuria
Babio, Nancy
Ortega-Azorin, Carolina
Castañer, Olga
Konieczna, Jadwiga
Notario Barandiaran, Leyre
Vaquero-Luna, Jessica
Benavente-Marín, Juan Carlos
Zulet, M. Angeles
Sanchez-Villegas, Almudena 
Sacanella, Emilio
Gómez Huelgas, Ricardo
Miró-Moriano, Leticia
Gimenez-Gracia, Mariano
Julibert, Alicia
Razquin, Cristina
Basora, Josep
Portolés, Olga
Goday, Albert
Galmés-Panadés, Aina M.
López-García, Carmen M.
Moreno-Rodriguez, Anai
Toledo, Estefanía
Díaz-López, Andrés
Fitó, Montserrat
Tinahones, Francisco J.
Bernal-López, M. Rosa
UNESCO Clasification: 32 Ciencias médicas
3206 Ciencias de la nutrición
Keywords: Type-2 Diabetes-Mellitus
Mediterranean Diet
Metabolic Syndrome
Physical-Activity
Cardiovascular-Disease, et al
Issue Date: 2020
Project: Efecto de la Dieta Mediterránea Hopocalórica y Promoción de la Actividad Física en Prevención Primaria Cardiovascular.Estudio Piloto Sobre Marcadores Intermedios. 
Efecto de Una Pérdida de Peso Con Dieta Mediterránea Hipocalórica y Promoción de la Actividad Física en la Prevención Primaria Cardiovascular 
Sistema Inmune Inespecífico en Dorada (Sparus Aurata): Activación Del Sistema Interferón y Papel de la Actividad Bh4. Pi042004/153 
Neuroprotección Por Bloqueo de la Capacidad de Transactivadora Nf-Kb y Factores Relacionados. 
Journal: Obesity 
Abstract: Objective: The hypertriglyceridemic waist (HTGW) phenotype is characterized by abdominal obesity and high levels of triglycerides. In a cross-sectional assessment of PREDIMED-Plus trial participants at baseline, HTGW phenotype prevalence was evaluated, associated risk factors were analyzed, and the lifestyle of individuals with metabolic syndrome and HTGW was examined. Methods: A total of 6,874 individuals aged 55 to 75 with BMI ≥ 27 and < 40 kg/m2 were included and classified by presence (HTGW+) or absence (HTGW−) of HTGW (waist circumference: men ≥ 102 cm, women ≥ 88 cm; fasting plasma triglycerides ≥ 150 mg/dL). Analytical parameters and lifestyle (energy intake and expenditure) were analyzed. Results: A total of 38.2% of the sample met HTGW+ criteria. HTGW+ individuals tended to be younger, have a greater degree of obesity, be sedentary, and be tobacco users. They had higher peripheral glucose, total cholesterol, and low-density lipoprotein cholesterol levels; had lower high-density lipoprotein cholesterol levels; and had increased prevalence of type 2 diabetes mellitus. Mediterranean diet (MedDiet) adherence and physical activity were greater in HTGW− patients. Age, BMI, tobacco use, total energy expenditure, hypertension, type 2 diabetes mellitus, and MedDiet adherence were associated with HTGW+. Conclusions: HTGW is a highly prevalent phenotype in this population associated with younger age, higher BMI, tobacco use, and decreased MedDiet adherence. HTGW− individuals were more physically active with greater total physical activity, and fewer had hypertension.
URI: http://hdl.handle.net/10553/70753
ISSN: 1930-7381
DOI: 10.1002/oby.22728
Source: Obesity [ISSN 1930-7381], v. 28 (3), p. 537-543
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