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Title: Objective comparison between platelet rich plasma alone and in combination with physical therapy in dogs with osteoarthritis caused by hip dysplasia
Authors: Cuervo, Belén
Rubio, Mónica
Chicharro, Deborah
Damiá, Elena
Santana Del Pino, Ángelo 
Carrillo, José María
Del Romero, Ayla
Vilar Guereño, José Manuel 
Cerón, José Joaquín
Sopena, Joaquín Jesús
UNESCO Clasification: 310907 Patología
Keywords: Biomarkers
Physical Therapy
Plasma Rich In Growth Factors, et al
Issue Date: 2020
Journal: Animals 
Abstract: Osteoarthritis (OA) is one of the most significant joint diseases worldwide. There are different therapies for OA treatment, and a relatively new strategy is the use of plasma rich in growth factors (PRGF), a platelet rich plasma (PRP) derivative. The objective of this study was to objectively assess the efficacy and duration of the effect of an intraarticular injection of PRGF and a combination of PRGF + physical therapy. The objective assessment was provided using a force platform. The obtained parameters were peak vertical force (PVF) and vertical impulse (VI). A total of 24 dogs with lameness and pain associated to OA attributable to bilateral hip dysplasia were included in the study. Animals were divided into two study groups and evaluated at baseline and at 30, 90, and 180 days after intraarticular PRGF or PRGF + physical therapy. Significant differences were observed at every checkpoint with respect to basal time in both groups. However, after 180 days, the PRGF group showed a decrease in PVF and VI with respect to the values obtained at 90 days. However, the PRGF + physical therapy group maintained increased values of both PVF and VI values during the 180-day study period.
ISSN: 2076-2615
DOI: 10.3390/ani10020175
Source: Animals [ISSN 2076-2615], v. 10 (2), 175
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