Study of non-specific reactive hepatitis in stray dogs

Abstract

The purpose of this paper was to study the possible causes of Non-Specific Reactive Hepatitis (NSRH) in tissue samples of housed dogs that were collected from different cities of Andalucia (Spain). Histologically, this disease was characterized by the presence of lymphocytes and plasma cells spread throughout the liver parenchyma and in the portal stroma, with no evidence of hepatocyte necrosis. These animals showed non-specific chronic reactive hepatitis that varied from moderate to severe. In order of prevalence, the more common pathologies associated with NSRH were gastrointestinal and renal diseases, as well as pneumonia mainly of parasitic or infectious origin.