Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/70007
Title: Yeast cells can partially revert chromosome segregation to repair late DNA double-strand breaks through homologous recombination
Authors: Ayra-Plasencia, Jessel
Machín, Félix
UNESCO Clasification: 320103 Microbiología clínica
Keywords: Chromosome Segregation
DNA Double-Strand Breaks
Homologous Recombination
Kinesin
Telophase
Issue Date: 2019
Journal: Molecular and Cellular Oncology 
Abstract: DNA repair in late mitosis sets paradoxical scenarios. Cyclin-dependent kinase (CDK) activity is high, which favors homologous recombination (HR), despite a sister chromatid is not physically close to recombine with. We have found that DNA double-strand breaks partially revert chromosome segregation to find an intact template and repair through HR.
URI: http://hdl.handle.net/10553/70007
ISSN: 2372-3556
DOI: 10.1080/23723556.2019.1648027
Source: Molecular and Cellular Oncology [ISSN 2372-3556], v. 6 (5), e1648027
Appears in Collections:Artículos
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