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http://hdl.handle.net/10553/70007
| Título: | Yeast cells can partially revert chromosome segregation to repair late DNA double-strand breaks through homologous recombination | Autores/as: | Ayra-Plasencia, Jessel Machín, Félix |
Clasificación UNESCO: | 320103 Microbiología clínica | Palabras clave: | Chromosome Segregation DNA Double-Strand Breaks Homologous Recombination Kinesin Telophase |
Fecha de publicación: | 2019 | Publicación seriada: | Molecular and Cellular Oncology | Resumen: | DNA repair in late mitosis sets paradoxical scenarios. Cyclin-dependent kinase (CDK) activity is high, which favors homologous recombination (HR), despite a sister chromatid is not physically close to recombine with. We have found that DNA double-strand breaks partially revert chromosome segregation to find an intact template and repair through HR. | URI: | http://hdl.handle.net/10553/70007 | ISSN: | 2372-3556 | DOI: | 10.1080/23723556.2019.1648027 | Fuente: | Molecular and Cellular Oncology [ISSN 2372-3556], v. 6 (5), e1648027 |
| Colección: | Artículos |
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