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Title: Adherence to a priori dietary indexes and baseline prevalence of cardiovascular risk factors in the PREDIMED-Plus randomised trial
Authors: Alvarez-Alvarez, Ismael
Toledo, Estefanía
Lecea, Oscar
Salas-Salvadó, Jordi
Corella, Dolores
Buil-Cosiales, Pilar
Zomeño, María Dolores
Vioque, Jesús
Martinez, J. Alfredo
Konieczna, Jadwiga
Barón-López, Francisco J.
López-Miranda, José
Estruch, Ramon
Bueno-Cavanillas, Aurora
Alonso-Gómez, Ángel M.
Tur, Josep A.
Tinahones, Francisco J.
Serra Majem, Luis 
Martín, Vicente
Ortega-Calvo, Manuel
Vázquez, Clotilde
Pintó, Xavier
Vidal, Josep
Daimiel, Lidia
Delgado-Rodríguez, Miguel
Matía, Pilar
González, José I.
Díaz-López, Andrés
Paz-Graniel, Indira
Muñoz, Miguel A.
Fito, Montse
Pertusa-Martinez, Salvador
Abete, Itziar
García-Ríos, Antonio
Ros, Emilio
Ruiz-Canela, Miguel
Martínez-González, Miguel
UNESCO Clasification: 320501 Cardiología
3206 Ciencias de la nutrición
Keywords: Dietary Pattern
Mediterranean Diet
Obesity, et al
Issue Date: 2019
Journal: European Journal of Nutrition 
Abstract: Cardiovascular disease remains the global leading cause of death. We evaluated at baseline the association between the adherence to eight a priori high-quality dietary scores and the prevalence of individual and clustered cardiovascular risk factors (CVRF) in the PREDIMED-Plus cohort. Methods All PREDIMED-Plus participants (6874 men and women aged 55-75 years, with overweight/obesity and metabolic syndrome) were assessed. The prevalence of 4 CVRF (hypertension, obesity, diabetes, and dyslipidaemia), using standard diagnoses criteria, were considered as outcomes. The adherence to eight a priori-defined dietary indexes was calculated. Multivariable models were fitted to estimate differences in mean values of factors and prevalence ratios for individual and clustered CVRF. Results Highest conformity to any dietary pattern did not show inverse associations with hypertension. The modified Mediterranean Diet Score (PR = 0.95; 95% CI 0.90-0.99), Mediterranean Diet Adherence Score (MEDAS) (PR = 0.94; 95% CI 0.89-0.98), the pro-vegetarian dietary pattern (PR = 0.95; 95% CI 0.90-0.99) and the Alternate Healthy Eating Index 2010 (PR = 0.92; 95% CI 0.87-0.96) were inversely associated with prevalence of obesity. We identified significant inverse trend among participants who better adhered to the MEDAS and the Prime Diet Quality Score (PDQS) in the mean number of CVRF across categories of adherence. Better adherence to several high-quality dietary indexes was associated with better blood lipid profiles and anthropometric measures. Conclusions Highest adherence to dietary quality indexes, especially Mediterranean-style and PDQS scores, showed marginal associations with lower prevalence of individual and clustered CVRF among elderly adults with metabolic syndrome at high risk of cardiovascular disease.
ISSN: 1436-6207
DOI: 10.1007/s00394-019-01982-x
Source: European Journal Of Nutrition [ISSN 1436-6207], v. 59 (3), p. 1219-1232, (Abril 2020)
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