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Title: In-vivo and ex-vivo tissue analysis through hyperspectral imaging techniques: Revealing the invisible features of cancer
Authors: Halicek, Martin
Fabelo Gómez, Himar Antonio 
Ortega Sarmiento, Samuel 
Marrero Callicó, Gustavo Iván 
Fei, Baowei
UNESCO Clasification: 3314 Tecnología médica
Keywords: Hyperspectral imaging
Clinical diagnosis
Biomedical optical imaging
Medical diagnostic imaging, et al
Issue Date: 2019
Project: Identificación Hiperespectral de Tumores Cerebrales (Ithaca)
Journal: Cancers (Basel) 
Abstract: In contrast to conventional optical imaging modalities, hyperspectral imaging (HSI) is able to capture much more information from a certain scene, both within and beyond the visual spectral range (from 400 to 700 nm). This imaging modality is based on the principle that each material provides different responses to light reflection, absorption, and scattering across the electromagnetic spectrum. Due to these properties, it is possible to differentiate and identify the different materials/substances presented in a certain scene by their spectral signature. Over the last two decades, HSI has demonstrated potential to become a powerful tool to study and identify several diseases in the medical field, being a non-contact, non-ionizing, and a label-free imaging modality. In this review, the use of HSI as an imaging tool for the analysis and detection of cancer is presented. The basic concepts related to this technology are detailed. The most relevant, state-of-the-art studies that can be found in the literature using HSI for cancer analysis are presented and summarized, both in-vivo and ex-vivo. Lastly, we discuss the current limitations of this technology in the field of cancer detection, together with some insights into possible future steps in the improvement of this technology.
ISSN: 2072-6694
DOI: 10.3390/cancers11060756
Source: Cancers (Basel) [ISSN 2072-6694], v. 11 (6), p. 756
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