|Title:||Seafood consumption, omega-3 fatty acids intake, and life-time prevalence of depression in the PREDIMED-plus trial||Authors:||Sánchez-Villegas, Almudena
Zomeño, Maria Dolores
Martínez, Jose Alfredo
Tur, Josep A.
Tinahones, Francisco J.
Muñoz, Miguel Ángel
de la Hera, Manoli García
Martínez-González, Miguel Ángel
|UNESCO Clasification:||3206 Ciencias de la nutrición||Keywords:||Physical-Activity Questionnaire
Metaanalysis, et al
|Issue Date:||2018||Project:||Efecto de la Dieta Mediterránea Hopocalórica y Promoción de la Actividad Física en Prevención Primaria Cardiovascular.Estudio Piloto Sobre Marcadores Intermedios.||Journal:||Nutrients||Abstract:||Background: The aim of this analysis was to ascertain the type of relationship between fish and seafood consumption, omega-3 polyunsaturated fatty acids (-3 PUFA) intake, and depression prevalence. Methods: Cross-sectional analyses of the PREDIMED-Plus trial. Fish and seafood consumption and -3 PUFA intake were assessed through a validated food-frequency questionnaire. Self-reported life-time medical diagnosis of depression or use of antidepressants was considered as outcome. Depressive symptoms were collected by the Beck Depression Inventory-II. Logistic regression models were used to estimate the association between seafood products and -3 PUFA consumption and depression. Multiple linear regression models were fitted to assess the association between fish and long-chain (LC) -3 PUFA intake and depressive symptoms. Results: Out of 6587 participants, there were 1367 cases of depression. Total seafood consumption was not associated with depression. The odds ratios (ORs) (95% confidence intervals (CIs)) for the 2nd, 3rd, and 4th quintiles of consumption of fatty fish were 0.77 (0.63-0.94), 0.71 (0.58-0.87), and 0.78 (0.64-0.96), respectively, and p for trend = 0.759. Moderate intake of total LC -3 PUFA (approximately 0.5-1 g/day) was significantly associated with a lower prevalence of depression. Conclusion: In our study, moderate fish and LC -3 PUFA intake, but not high intake, was associated with lower odds of depression suggesting a U-shaped relationship.||URI:||http://hdl.handle.net/10553/55017||ISSN:||2072-6643||DOI:||10.3390/nu10122000||Source:||Nutrients [ISSN 2072-6643], v. 10 (12), (Diciembre 2018)|
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