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Title: Assessment of muscle wasting in long-stay ICU patients using a new ultrasound protocol
Authors: Hernández-Socorro, Carmen Rosa 
Saavedra, Pedro
López-Fernández, Juan Carlos 
Ruiz Santana, Sergio 
UNESCO Clasification: 32 Ciencias médicas
Keywords: Ultrasound
Muscle weakness
Muscle mass
Critical illness
Bayesian prediction, et al
Issue Date: 2018
Journal: Nutrients 
Abstract: There is currently no standardized procedure to assess sarcopenia in long-stay catabolic patients. Our aim is to analyze a novel ultrasound muscle assessment protocol in these patients versus healthy controls, by carrying out a prospective observational study. We designed a new ultrasound protocol that assesses quadriceps rectus femoris (QRF) muscle quality in real-time B-mode, color-Doppler, and M-mode ultrasound, and evaluates QRF intramuscular central tendon thickness, cross-sectional area, and muscle thickness in ultrasound B-mode. Logistic regression was performed as a multivariable analysis on 29 cases and 19 controls. The QRF muscle area and thickness were shown to significantly decrease (p 0.001), and the central tendon thickness significantly increased (p = 0.047) in cases versus controls. The QRF muscle echogenicity and angiogenic activity fasciculations, subcutaneous edema, and intramuscular fluid were also significantly different between the two groups (p < 0.001). The selected variables in the multivariate logit analysis were the muscle area (OR per cm2 = 0.07; 95% confidence interval (CI) = 0.012–0.41) and the central tendon thickness (OR per mm 1.887; 95% CI = 2.66–13.38).
ISSN: 2072-6643
DOI: 10.3390/nu10121849
Source: Nutrients [ISSN 2072-6643],v. 10 (12), 1249, p. 1-11
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