Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/54991
DC FieldValueLanguage
dc.contributor.authorLuzardo, Octavio P.en_US
dc.contributor.authorBadea, Mihaelaen_US
dc.contributor.authorZumbado, Manuelen_US
dc.contributor.authorRogozea, Lilianaen_US
dc.contributor.authorFloroian, Lauraen_US
dc.contributor.authorIlea, Ancaen_US
dc.contributor.authorMoga, Mariusen_US
dc.contributor.authorSechel, Gabrielaen_US
dc.contributor.authorBoada, Luis D.en_US
dc.contributor.authorHenríquez-Hernández, Luis Albertoen_US
dc.date.accessioned2019-02-18T16:02:43Z-
dc.date.available2019-02-18T16:02:43Z-
dc.date.issued2019en_US
dc.identifier.issn0048-9697en_US
dc.identifier.urihttp://hdl.handle.net/10553/54991-
dc.description.abstractPersistent organochlorine pollutants (POPs) are highly lipophilic and resistant to degradation, hence these substances are commonly found in the environment even decades after their prohibition. The aim of the present study was to determine human serum concentrations of POPs and polycyclic aromatic hydrocarbons (PAHs) in the Romanian population, investigating the role of demographic variables on the body burden of such chemicals. A cross-sectional study including a total of 121 subjects from Brasov (Transylvania region) was designed. The concentration of 62 chemicals, including organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs), polybrominated diphenyl ethers (BDEs) and PAHs, was measured by gas chromatography–mass spectrometry (GC–MS) in the serum of the participants. p,p′-DDE and β-HCH were detected in 100% and 62% of the series (median values = 2.1 and 0.5 μg/L); PCB-153 was detected in 77.7% of the subjects and PCB-28 showed the highest median concentration (0.5 μg/L); BDE-47 was detected at a low concentration in 11.6% of the individuals; phenanthrene and naphthalene were present in 98.3% and 38.8% of the serum samples (median values = 0.9 and 6.5 μg/L, respectively). Age was the main determinant of the total body burden of OCPs and PCBs. A positive correlation was observed between p,p′-DDE and age (Spearman Rho = 0.312, P < 0.0001), suggesting the prevalence of higher levels of pollutants at older ages. The present results showed a significant decrease in serum levels of p,p′-DDE and HCH in Romania —a country which has traditionally reported higher values than other Eastern European countries— as well as low levels of PCBs and BDEs. The presence of PAHs suggests an unknown source of exposure that deserves further investigation.en_US
dc.languageengen_US
dc.publisher0048-9697-
dc.relation.ispartofScience of the Total Environmenten_US
dc.sourceScience of the Total Environment [ISSN 0048-9697], v. 656, p. 709-716en_US
dc.subject32 Ciencias médicasen_US
dc.subject.otherHuman serumen_US
dc.subject.otherOrganochlorine pesticidesen_US
dc.subject.otherPolychlorinated biphenylsen_US
dc.subject.otherPolybrominated diphenyl ethersen_US
dc.subject.otherPolycyclic aromatic hydrocarbonsen_US
dc.subject.otherRomaniaen_US
dc.titleBody burden of organohalogenated pollutants and polycyclic aromatic hydrocarbons in Romanian population: Influence of age, gender, body mass index, and habitaten_US
dc.typeinfo:eu-repo/semantics/Articleen_US
dc.typeArticleen_US
dc.identifier.doi10.1016/j.scitotenv.2018.11.404
dc.identifier.scopus85057838951
dc.identifier.isi000455039600069
dc.contributor.authorscopusid6507534124
dc.contributor.authorscopusid57203867918
dc.contributor.authorscopusid6603459604
dc.contributor.authorscopusid25723728400
dc.contributor.authorscopusid25723181600
dc.contributor.authorscopusid37050762200
dc.contributor.authorscopusid24468455300
dc.contributor.authorscopusid39862024300
dc.contributor.authorscopusid6603916807
dc.contributor.authorscopusid15829708200
dc.description.lastpage716-
dc.description.firstpage709-
dc.relation.volume656-
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.contributor.daisngid418704
dc.contributor.daisngid167016
dc.contributor.daisngid418822
dc.contributor.daisngid2235034
dc.contributor.daisngid1597650
dc.contributor.daisngid6507089
dc.contributor.daisngid662800
dc.contributor.daisngid7434675
dc.contributor.daisngid1656886
dc.contributor.daisngid30144524
dc.contributor.wosstandardWOS:Luzardo, OP
dc.contributor.wosstandardWOS:Badea, M
dc.contributor.wosstandardWOS:Zumbadoa, M
dc.contributor.wosstandardWOS:Rogozea, L
dc.contributor.wosstandardWOS:Floroian, L
dc.contributor.wosstandardWOS:Ilea, A
dc.contributor.wosstandardWOS:Moga, M
dc.contributor.wosstandardWOS:Sechel, G
dc.contributor.wosstandardWOS:Boada, LD
dc.contributor.wosstandardWOS:Henriquez-Hernandez, LA
dc.date.coverdateMarzo 2019
dc.identifier.ulpgces
dc.description.sjr1,661
dc.description.jcr6,551
dc.description.sjrqQ1
dc.description.jcrqQ1
dc.description.scieSCIE
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.author.deptGIR IUIBS: Medio Ambiente y Salud-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Clínicas-
crisitem.author.deptGIR IUIBS: Medio Ambiente y Salud-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Clínicas-
crisitem.author.deptGIR IUIBS: Medio Ambiente y Salud-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Clínicas-
crisitem.author.deptGIR IUIBS: Medio Ambiente y Salud-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Clínicas-
crisitem.author.orcid0000-0002-4153-3028-
crisitem.author.orcid0000-0002-1534-7758-
crisitem.author.orcid0000-0002-0195-4565-
crisitem.author.orcid0000-0003-3237-0316-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNamePérez Luzardo, Octavio Luis-
crisitem.author.fullNameZumbado Peña, Manuel Luis-
crisitem.author.fullNameDomínguez Boada, Luis María-
crisitem.author.fullNameHenríquez Hernández, Luis Alberto-
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