Please use this identifier to cite or link to this item:
http://hdl.handle.net/10553/53990
Title: | Application of microwave-assisted extraction and ultra-high performance liquid chromatography-tandem mass spectrometry for the analysis of sex hormones and corticosteroids in sewage sludge samples | Authors: | Guedes-Alonso, Rayco Santana-Viera, Sergio Montesdeoca-Esponda, Sarah Afonso-Olivares, Cristina Sosa-Ferrera, Zoraida Santana-Rodríguez, José Juan |
UNESCO Clasification: | 2302 Bioquímica 2391 Química ambiental |
Keywords: | Mass spectrometry Microwave-assisted extraction Sludge Steroid hormones Ultra-high performance liquid chromatography |
Issue Date: | 2016 | Publisher: | 1618-2642 | Project: | Estrategias Para El Control y Remediación Natural de Compuestos Orgánicos Emergentes en Aguas Residuales. Impacto en El Medio Marino. | Journal: | Analytical and Bioanalytical Chemistry | Abstract: | Hormonal compounds are a concern to the international community because they can affect the aquatic biota and are therefore considered to be endocrine-disrupting compounds. These compounds have lipophilic properties, so they tend to accumulate in solid matrices, such as sewage sludge. This work presents the optimization of a microwave-assisted extraction process combined with ultra-high performance liquid chromatography–tandem mass spectrometry for the determination of 15 hormonal compounds in sludge samples. The proposed method has relative standard deviations below 23 %, good recoveries (over 71 %) for all compounds, detection limits that ranged from 1.1 to 7.9 ng g−1 and quantification limits which ranged from 3.7 to 26.3 ng g−1. The method was used to analyse sludge samples from four different wastewater treatment plants of Gran Canaria (Spain) with different wastewater treatments. 17β-estradiol, 17α-ethynylestradiol, norgestrel and cortisone were detected in sludge samples at concentrations that ranged from 17.3 to 1.44 × 103 ng g−1. The developed method permits the use of small quantities of sample and organic solvents, presents short extractions times and is the first one based on microwave-assisted extraction for the analysis of both sex hormones and corticosteroids. | URI: | http://hdl.handle.net/10553/53990 | ISSN: | 1618-2642 | DOI: | 10.1007/s00216-016-9810-7 | Source: | Analytical and Bioanalytical Chemistry [ISSN 1618-2642], Septiembre 2016, v. 408 (24), p. 6833-6844 |
Appears in Collections: | Artículos |
SCOPUSTM
Citations
23
checked on Mar 30, 2025
WEB OF SCIENCETM
Citations
18
checked on Mar 30, 2025
Page view(s)
149
checked on Jan 11, 2025
Download(s)
38
checked on Jan 11, 2025
Google ScholarTM
Check
Altmetric
Share
Export metadata
Items in accedaCRIS are protected by copyright, with all rights reserved, unless otherwise indicated.