Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/52998
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dc.contributor.authorRodriguez Esparragon, Francisco
dc.contributor.authorCompanioni, Osmel
dc.contributor.authorGarcia Bello, Miguel
dc.contributor.authorBuset Rios, Nisa
dc.contributor.authorRodriguez Perez, Jose Carlos
dc.contributor.otherRodriguez-Perez, J.C.
dc.contributor.otherRodriguez-Esparragon, Francisco
dc.contributor.otherGarcia-Bello, Miguel-Angel
dc.date.accessioned2019-02-04T14:40:05Z-
dc.date.available2019-02-04T14:40:05Z-
dc.date.issued2012
dc.identifier.issn0278-0240
dc.identifier.urihttp://hdl.handle.net/10553/52998-
dc.description.abstractRecent genome-wide single nucleotide polymorphism (SNP) association studies (GWAS) have identified a number of SNPs that were significantly associated with coronary artery disease (CAD) and myocardial infarction (MI). We tested for replication of the previously described association with CAD in our case-control datasets of SNPs variants located at 1p13.1, 2q33.1, 10q11.1, 9p21, and 21q22. We observed a small significant risk associated of the SNP rs10757274 with CAD in the PROCAGENE study. Besides, the multilocus combination rs10757274 and rs1333048 gave a near significant result. We confirmed that the SNP rs10757274 showed association with CAD in the PROCAGENE study, although after applying the Bonferroni correction was not longer significant. Independent replication studies in other populations are needed to unequivocally confirm the association.
dc.publisher0278-0240
dc.relation.ispartofDisease Markers
dc.sourceDisease Markers[ISSN 0278-0240],v. 32 (4), p. 231-239
dc.subject.otherCoronary-Artery-Disease
dc.subject.otherSingle-Nucleotide Polymorphisms
dc.subject.otherMyocardial-Infarction
dc.subject.otherGene Polymorphisms
dc.subject.otherChromosome 9P21.3
dc.subject.otherHeart-Disease
dc.subject.otherRisk
dc.subject.otherAtherosclerosis
dc.subject.otherHypertension
dc.subject.otherExpression
dc.titleReplication of relevant SNPs associated with cardiovascular disease susceptibility obtained from GWAs in a case-control study in a Canarian population
dc.typeinfo:eu-repo/semantics/Article
dc.typeArticle
dc.identifier.doi10.3233/DMA-2011-0879
dc.identifier.scopus84859337186
dc.identifier.isi000301947100003
dcterms.isPartOfDisease Markers
dcterms.sourceDisease Markers[ISSN 0278-0240],v. 32 (4), p. 231-239
dc.contributor.authorscopusid6504727864
dc.contributor.authorscopusid14061836500
dc.contributor.authorscopusid55172451900
dc.contributor.authorscopusid53464098000
dc.contributor.authorscopusid57212029793
dc.description.lastpage239
dc.identifier.issue4
dc.description.firstpage231
dc.relation.volume32
dc.type2Artículo
dc.identifier.wosWOS:000301947100003
dc.contributor.daisngid1305938
dc.contributor.daisngid2952487
dc.contributor.daisngid4949467
dc.contributor.daisngid1700450
dc.contributor.daisngid3498770
dc.contributor.daisngid245684
dc.identifier.investigatorRIDC-1247-2010
dc.identifier.investigatorRIDD-2810-2013
dc.identifier.investigatorRIDNo ID
dc.contributor.wosstandardWOS:Esparragon, FR
dc.contributor.wosstandardWOS:Companioni, O
dc.contributor.wosstandardWOS:Bello, MG
dc.contributor.wosstandardWOS:Rios, NB
dc.contributor.wosstandardWOS:Perez, JCR
dc.date.coverdateEnero 2012
dc.identifier.ulpgces
dc.description.sjr0,843
dc.description.jcr2,14
dc.description.sjrqQ2
dc.description.jcrqQ2
item.fulltextSin texto completo-
item.grantfulltextnone-
crisitem.author.deptPatología médica-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptCiencias Médicas y Quirúrgicas-
crisitem.author.orcid0000-0003-1663-3673-
crisitem.author.orcid0000-0003-0023-1063-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameRodríguez Esparragón, Francisco Javier-
crisitem.author.fullNameRodríguez Pérez, José Carlos-
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