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Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/52567
DC FieldValueLanguage
dc.contributor.authorCastillo, Q.A.en_US
dc.contributor.authorTriana, Jorgeen_US
dc.contributor.authorEiroa, José Luisen_US
dc.contributor.authorCalcul, L.en_US
dc.contributor.authorRivera, E.en_US
dc.contributor.authorWojtas, L.en_US
dc.contributor.authorPadrón, J.M.en_US
dc.contributor.authorBoberieth, L.en_US
dc.contributor.authorKeramane, M.en_US
dc.contributor.authorAbel-Santos, E.en_US
dc.contributor.authorBáez, L.A.en_US
dc.contributor.authorGermosén, E.A.en_US
dc.date.accessioned2018-11-30T14:02:51Z-
dc.date.available2018-11-30T14:02:51Z-
dc.date.issued2016en_US
dc.identifier.issn0163-3864en_US
dc.identifier.urihttp://hdl.handle.net/10553/52567-
dc.description.abstractSix new ent-labdane diterpenoids, uasdlabdanes A-F (1-6), were isolated from the aerial parts of Eupatorium obtusissmum. The new structures were elucidated through spectroscopic and spectrometric data analyses. The absolute configurations of compounds 1 and 2 were established by X-ray crystallography, and those of 3-6, by comparison of experimental and calculated electronic circular dichroism spectra. The antiproliferative activity of the compounds was studied in a panel of six representative human solid tumor cell lines and showed GI50 values ranging from 19 to >100 μM.en_US
dc.languageengen_US
dc.relation.ispartofJournal of Natural Productsen_US
dc.sourceJournal of Natural Products [ISSN 0163-3864], v. 79 (4), p. 907-913en_US
dc.subject2302 Bioquímicaen_US
dc.subject.otherAbsolute-Configuration
dc.titleEnt-Labdane diterpenoids from the aerial parts of eupatorium obtusissmumen_US
dc.typeinfo:eu-repo/semantics/Articlees
dc.typeArticlees
dc.identifier.doi10.1021/acs.jnatprod.5b00954
dc.identifier.scopus84966737750
dc.identifier.isi000374915800031
dc.contributor.authorscopusid55891218100
dc.contributor.authorscopusid55946071500
dc.contributor.authorscopusid6507583429
dc.contributor.authorscopusid6505661594
dc.contributor.authorscopusid57189270294
dc.contributor.authorscopusid11840381500
dc.contributor.authorscopusid7003856521
dc.contributor.authorscopusid57189264199
dc.contributor.authorscopusid57189265332
dc.contributor.authorscopusid6506088282
dc.contributor.authorscopusid57205743085
dc.contributor.authorscopusid57189266327
dc.description.lastpage913-
dc.identifier.issue4-
dc.description.firstpage907-
dc.relation.volume79-
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.contributor.daisngid9976720
dc.contributor.daisngid1400733
dc.contributor.daisngid2831014
dc.contributor.daisngid2684646
dc.contributor.daisngid20600850
dc.contributor.daisngid150950
dc.contributor.daisngid254427
dc.contributor.daisngid32475526
dc.contributor.daisngid25914087
dc.contributor.daisngid1492341
dc.contributor.daisngid32234633
dc.contributor.daisngid23366789
dc.contributor.wosstandardWOS:Castillo, QA
dc.contributor.wosstandardWOS:Triana, J
dc.contributor.wosstandardWOS:Eiroa, JL
dc.contributor.wosstandardWOS:Calcul, L
dc.contributor.wosstandardWOS:Rivera, E
dc.contributor.wosstandardWOS:Wojtas, L
dc.contributor.wosstandardWOS:Padron, JM
dc.contributor.wosstandardWOS:Boberieth, L
dc.contributor.wosstandardWOS:Keramane, M
dc.contributor.wosstandardWOS:Abel-Santos, E
dc.contributor.wosstandardWOS:Baez, LA
dc.contributor.wosstandardWOS:Germosen, EA
dc.date.coverdateAbril 2016
dc.identifier.ulpgcSíes
dc.description.sjr1,22
dc.description.jcr3,281
dc.description.sjrqQ1
dc.description.jcrqQ1
dc.description.scieSCIE
item.fulltextSin texto completo-
item.grantfulltextnone-
crisitem.author.deptGIR IUIBS: Bioquímica-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.orcid0000-0002-4986-8332-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameEiroa Martínez,José Luis-
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