Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/52564
Title: Radiotherapy for Graves' disease. The possible role of low-dose radiotherapy
Authors: Arenas, Meritxell
Sabater, Sebastià
Lara Jiménez, Pedro Carlos 
Rovirosa, Àngels
Biete, Albert
Linares, Victoria
Belles, Montse
Panés, Julià
UNESCO Clasification: 32 Ciencias médicas
Keywords: Graves' ophthalmopathy
Low-dose radiotherapy
Radiotherapy for benign disease
Issue Date: 2016
Journal: Reports of Practical Oncology and Radiotherapy 
Abstract: Immunomodulatory effects of low-dose radiotherapy (LD-RT) have been used for the treatment of several benign diseases, including arthrodegenerative and inflammatory pathologies. Graves' disease is an autoimmune disease and radiotherapy (RT) is a therapeutic option for ocular complications. The dose recommended in the clinical practice is 20 Gy (2 Gy/day). We hypothesized that lower doses (<10 Gy total dose, <1 Gy/day) could results in higher efficacy if we achieved anti-inflammatory and immunomodulatory effects of LD-RT.We review current evidence on the effects of RT in the treatment of Graves' disease and the possible use of LD-RT treatment strategy.
URI: http://hdl.handle.net/10553/52564
ISSN: 1507-1367
DOI: 10.1016/j.rpor.2016.02.001
Source: Reports of Practical Oncology and Radiotherapy [ISSN 1507-1367], v. 21 (3), p. 213-218
Appears in Collections:Reseña
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