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http://hdl.handle.net/10553/51935
Title: | Effects of fibrin on the integration hydroxyapatite coating implants: Experimental study in a rabbit model | Authors: | Morales, M. Navarro, R. Almenara, M. Medina, J. M. Melian, C. Gutierrez, C |
Keywords: | Osteogenic Response Long-Term Bone Sealant Dogs, et al |
Issue Date: | 2002 | Publisher: | 0939-8600 | Journal: | Journal of Experimental Animal Science | Abstract: | The purpose of this study was to investigate the effects of the addition of fibrin (SAF) to titanium alloy implants coated with hydroxyapatite (HAP) on osteogenesis in rabbits. A titanium (Ti) alloy implant was inserted into the femoral neck of twenty-four adult rabbits. Six rabbits were included on each of the following groups: Ti control, HAP-coated Ti Module, HAP-coated Ti nodule with added fibrin glue and Ti module also with added fibrin glue. After seven weeks, bone growth was examined radiographically and by histo-morphometry. The SAF/HAP mixture did caused to a significant increase in bone growth compared to the other groups. The addition of fibrin did not result in an increase in new-bone growth and increase the formation of fibrous tissue in contact with the implant. We concluded that SAF did not demonstrate osteoinductive properties. | URI: | http://hdl.handle.net/10553/51935 | ISSN: | 0939-8600 | Source: | Journal Of Experimental Animal Science[ISSN 0939-8600],v. 42 (2), p. 102-112 |
Appears in Collections: | Artículos |
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