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Title: New antagonist agents of neuropeptide Y receptors
Authors: Aldana, Ignacio
Rivero, Isabel
Rivero, Argimiro 
Huenchuñir, Patricio
Frigola, Carmen
Alonso, Maria Luisa
Monge, Antonio
Caignard, D. H.
Renard, P.
UNESCO Clasification: 2306 Química orgánica
Keywords: Obesity
Energy metabolism
Weight reduction
Neuropeptide Y
Issue Date: 2000
Publisher: 0100-4042
Journal: Química Nova 
Abstract: In the CNS, NPY has been implicated in obesity and feeding, endocrine function and metabolism. Potent and selective rNPY antagonists will be able to probe the merits of this approach for the treatment of obesity. We report the synthesis and preliminary evaluation of some hydrazide derivatives as antagonists of rNPY.
ISSN: 0100-4042
DOI: 10.1590/S0100-40422000000600005
Source: Quimica Nova [ISSN 0100-4042], v. 23, p. 737-741
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