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Title: Clinicopathological Features of Hemangioma in Two Young Horses
Authors: Zafra, Rafael
Estepa, José Carlos
Aguilera-Tejero, Escolástico
Jaber, José Raduán 
Bautista, María José
Pacheco, Isabel
Pérez, José
Keywords: Skin
Issue Date: 2012
Publisher: 0737-0806
Journal: Journal of Equine Veterinary Science 
Abstract: The clinicopathological and immunohistochemical features of two vascular tumors in two young horses are described in the present work. These animals were referred to the Veterinary Teaching Hospital of the University of Cordoba because of the presence of hyperpigmented plaques located in the medial aspect of the left leg and also around the hock (case 1) and in the right front leg (case 2). Some of the lesions showed deep ulceration and severe protrusion with abundant bleeding. The histopathological study revealed that lesions were composed of nonencapsulated, proliferated, closely packed small blood vessels, some of which showed irregular shape, whereas others were similar to capillaries, arterioles, and venules. Neoplastic cells expressed vimentin and factor VIllar, suggesting their endothelial nature, whereas in the wall of some proliferated vessels, some cells expressed vimentin, alpha-smooth muscle actin and desmin, an immunophenotype consistent with pericytes, and small muscle cells. These features agree with those reported in human juvenile hemangioma rather than with hemangioma in adult horses. (C) 2012 Elsevier Inc. All rights reserved.
ISSN: 0737-0806
DOI: 10.1016/j.jevs.2012.02.017
Source: Journal of Equine Veterinary Science[ISSN 0737-0806],v. 32, p. 767-769
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